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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H32FO9P
Molecular Weight 514.4776
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIAMCINOLONE ACETONIDE 21-DIHYDROGEN PHOSPHATE

SMILES

CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)COP(O)(O)=O

InChI

InChIKey=NXLTXRVPGUCAHF-JNQJZLCISA-N
InChI=1S/C24H32FO9P/c1-20(2)33-19-10-16-15-6-5-13-9-14(26)7-8-21(13,3)23(15,25)17(27)11-22(16,4)24(19,34-20)18(28)12-32-35(29,30)31/h7-9,15-17,19,27H,5-6,10-12H2,1-4H3,(H2,29,30,31)/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

HIDE SMILES / InChI

Description

Triamcinolone acetonide- 21-dihydrogen phosphate is the long-acting derivative of a synthetic glucocorticoid triamcinolone. Triamcinolone acetonide has eight times more potency than prednisolone. Triamcinolone acetonide- 21-dihydrogen phosphate used for intravenous injection. It is supposed to be hydrolyzed rapidly in the body to form the free corticoid alcohol.

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of the hypothalamic-pituitary-adrenal axis susceptibility upon single-dose i.m. depot versus long-acting i.v. triamcinolone acetonide therapy: a direct pharmacokinetic correlation.
2006 Nov

Sample Use Guides

In Vivo Use Guide
Single injection - 0.2 mg/kg
Route of Administration: Intravenous
Name Type Language
TRIAMCINOLONE ACETONIDE 21-DIHYDROGEN PHOSPHATE
Common Name English
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11-HYDROXY-16,17-((1-METHYLETHYLIDENE)BIS(OXY))-21-(PHOSPHONOOXY)-, (11.BETA.,16.ALPHA.)-
Common Name English
TRIAMCINOLONE ACETONIDE 21-PHOSPHATE
Common Name English
Code System Code Type Description
PUBCHEM
13809
Created by admin on Tue Oct 22 19:50:25 UTC 2019 , Edited by admin on Tue Oct 22 19:50:25 UTC 2019
PRIMARY
CAS
989-96-8
Created by admin on Tue Oct 22 19:50:25 UTC 2019 , Edited by admin on Tue Oct 22 19:50:25 UTC 2019
PRIMARY
ECHA (EC/EINECS)
213-587-5
Created by admin on Tue Oct 22 19:50:25 UTC 2019 , Edited by admin on Tue Oct 22 19:50:25 UTC 2019
PRIMARY