Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C30H48O6 |
| Molecular Weight | 504.6985 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@]5([H])[C@H](O)C[C@@]34C)C(O)=O
InChI
InChIKey=IDQVFXZQPGAVAM-GGVBUJAJSA-N
InChI=1S/C30H48O6/c1-25(2)9-11-30(24(35)36)12-10-28(5)17(18(30)13-25)7-8-21-26(3)14-20(33)23(34)27(4,16-31)22(26)19(32)15-29(21,28)6/h7,18-23,31-34H,8-16H2,1-6H3,(H,35,36)/t18-,19+,20+,21+,22+,23-,26+,27-,28+,29+,30-/m0/s1
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24697659
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24697659
Centella asiatica (L. ) Urban is a tropical medicinal plant with a long history of therapeutic uses. Terminolic acid, is a constituent of Centella asiatica, significantly decreases interleukin-8 production in human colon cancer cells. In addition, its inhibitory activity of against promyelocytic leukemia HL-60 and human erythromyeloblastoid leukemia K562 cell lines was also evaluated. It was found, that terminolic acid possesses moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Separation and determination of madecassic acid in triterpenic genins of Centella asiatica by high performance liquid chromatography using beta-cyclodextrin as mobile phase additive]. | 2007 May |
|
| Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. | 2016 Apr |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
9Z1542R0IT
Created by
admin on Sat Dec 16 09:54:37 GMT 2023 , Edited by admin on Sat Dec 16 09:54:37 GMT 2023
|
PRIMARY | |||
|
564-13-6
Created by
admin on Sat Dec 16 09:54:37 GMT 2023 , Edited by admin on Sat Dec 16 09:54:37 GMT 2023
|
PRIMARY | |||
|
12314613
Created by
admin on Sat Dec 16 09:54:37 GMT 2023 , Edited by admin on Sat Dec 16 09:54:37 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD
