| Stereochemistry | ABSOLUTE |
| Molecular Formula | C30H48O6 |
| Molecular Weight | 504.6985 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@]5([H])[C@H](O)C[C@@]34C)C(O)=O
InChI
InChIKey=IDQVFXZQPGAVAM-GGVBUJAJSA-N
InChI=1S/C30H48O6/c1-25(2)9-11-30(24(35)36)12-10-28(5)17(18(30)13-25)7-8-21-26(3)14-20(33)23(34)27(4,16-31)22(26)19(32)15-29(21,28)6/h7,18-23,31-34H,8-16H2,1-6H3,(H,35,36)/t18-,19+,20+,21+,22+,23-,26+,27-,28+,29+,30-/m0/s1
Centella asiatica (L. ) Urban is a tropical medicinal plant with a long history of therapeutic uses. Terminolic acid, is a constituent of Centella asiatica, significantly decreases interleukin-8 production in human colon cancer cells. In addition, its inhibitory activity of against promyelocytic leukemia HL-60 and human erythromyeloblastoid leukemia K562 cell lines was also evaluated. It was found, that terminolic acid possesses moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
SUBSTANCE RECORD
