Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C30H48O6 |
| Molecular Weight | 504.6985 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@]5([H])[C@H](O)C[C@@]34C)C(O)=O
InChI
InChIKey=IDQVFXZQPGAVAM-GGVBUJAJSA-N
InChI=1S/C30H48O6/c1-25(2)9-11-30(24(35)36)12-10-28(5)17(18(30)13-25)7-8-21-26(3)14-20(33)23(34)27(4,16-31)22(26)19(32)15-29(21,28)6/h7,18-23,31-34H,8-16H2,1-6H3,(H,35,36)/t18-,19+,20+,21+,22+,23-,26+,27-,28+,29+,30-/m0/s1
| Molecular Formula | C30H48O6 |
| Molecular Weight | 504.6985 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24697659
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24697659
Centella asiatica (L. ) Urban is a tropical medicinal plant with a long history of therapeutic uses. Terminolic acid, is a constituent of Centella asiatica, significantly decreases interleukin-8 production in human colon cancer cells. In addition, its inhibitory activity of against promyelocytic leukemia HL-60 and human erythromyeloblastoid leukemia K562 cell lines was also evaluated. It was found, that terminolic acid possesses moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Separation and determination of madecassic acid in triterpenic genins of Centella asiatica by high performance liquid chromatography using beta-cyclodextrin as mobile phase additive]. | 2007 May |
|
| Chemical constituents from Melastoma dodecandrum and their inhibitory activity on interleukin-8 production in HT-29 cells. | 2014 |
|
| Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. | 2016 Apr |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:54:37 UTC 2023
by
admin
on
Sat Dec 16 09:54:37 UTC 2023
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| Record UNII |
9Z1542R0IT
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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9Z1542R0IT
Created by
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564-13-6
Created by
admin on Sat Dec 16 09:54:37 UTC 2023 , Edited by admin on Sat Dec 16 09:54:37 UTC 2023
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12314613
Created by
admin on Sat Dec 16 09:54:37 UTC 2023 , Edited by admin on Sat Dec 16 09:54:37 UTC 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Constituent of Centella asiatica aerial parts.
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