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Details

Stereochemistry RACEMIC
Molecular Formula C8H8O
Molecular Weight 120.1485
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STYRENE OXIDE

SMILES

C1OC1C2=CC=CC=C2

InChI

InChIKey=AWMVMTVKBNGEAK-UHFFFAOYSA-N
InChI=1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2

HIDE SMILES / InChI

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity.
2005-06
Size control of styrene oxide-ethylene oxide diblock copolymer aggregates with classical surfactants: DLS, TEM, and ITC study.
2005-05-10
Multistate reactivity in styrene epoxidation by compound I of cytochrome p450: mechanisms of products and side products formation.
2005-04-22
Solubilisation in aqueous micellar solutions of block copoly(oxyalkylene)s.
2005-04-11
Quantitative measurement of DNA adducts using neutral hydrolysis and LC-MS. Validation of genotoxicity sensors.
2005-04-01
Ring-oxidized metabolites of styrene contribute to styrene-induced Clara-cell toxicity in mice.
2005-02-13
Analysis of oxidative stress in SK-N-MC neurons exposed to styrene-7,8-oxide.
2005-02
Comparison of the depletion of glutathione in mouse liver and lung following administration of styrene and its metabolites styrene oxide and 4-vinylphenol.
2005-01-31
Purification and characterization of a yeast carbonyl reductase for synthesis of optically active (R)-styrene oxide derivatives.
2005-01
Review of the in vivo genotoxicity tests performed with styrene.
2005-01
Styrene oxide DNA adducts: quantitative determination using 31P monitoring.
2005-01
A new role for glutathione: protection of vitamin B12 from depletion by xenobiotics.
2004-12
Styrene 7,8-oxide induces mitochondrial damage and oxidative stress in neurons.
2004-09-01
Direct electrochemiluminescence detection of oxidized DNA in ultrathin films containing [Os(bpy)2(PVP)10]2+.
2004-07-21
Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice.
2004-06-25
An efficient synthesis of 2-amino alcohols by silica gel catalysed opening of epoxide rings by amines.
2004-05-07
Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide.
2004-05-02
Donor ligand effect on the nature of the oxygenating species in Mn(III)(salen)-catalyzed epoxidation of olefins: experimental evidence for multiple active oxidants.
2004-04-19
Unique reactions of glycosyl iodides with oxa- and thiocycloalkane acceptors.
2004-03-18
Mechanistic approaches for evaluating the toxicity of reactive organochlorines and epoxides in green algae.
2004-03
Colorimetric high-throughput assay for alkene epoxidation catalyzed by cytochrome P450 BM-3 variant 139-3.
2004-03
Two-sample scale tests for comparison of metabolic rates for styrene in previously exposed and unexposed groups.
2004-02-28
[Neurotoxic effect of 7,8-oxide styrene on striatal neuron culture].
2004-02-26
Enantioselective hydrolysis of various substituted styrene oxides with Aspergillus Niger CGMCC 0496.
2004-02-07
A recombinant model for assessing the role of GSTM1 in styrene-7,8-oxide toxicity and mutagenicity.
2004-01-15
A novel approach based on solid phase microextraction gas chromatography and mass spectrometry to the determination of highly reactive organic compounds in cells cultures: styrene oxide.
2004-01
Influence of genetic polymorphisms on biomarkers of exposure and genotoxic effects in styrene-exposed workers.
2004
Epoxide-opening and group-transfer reactions mediated by monomeric zirconium imido complexes.
2003-11-26
Evaluation of bioanalytical assays for toxicity assessment and mode of toxic action classification of reactive chemicals.
2003-11-01
[Definition of neurotoxic risk based on the benchmark dose in vitro: illustration with experimental models based on the use of known neurotoxic substances].
2003-10-30
Refinements to physiologically-based pharmacokinetic model for styrene.
2003-09-30
Kinetics and mechanism of rhenium-catalyzed O atom transfer from epoxides.
2003-09-10
Voltammetric sensor for chemical toxicity using [Ru(bpy)2poly(4-vinylpyridine)10Cl)+ as catalyst in ultrathin films. DNA damage from methylating agents and an enzyme-generated epoxide.
2003-08-15
Enzymatic transformations. Immobilized A. niger epoxide hydrolase as a novel biocatalytic tool for repeated-batch hydrolytic kinetic resolution of epoxides.
2003-08-07
Association properties of ethylene oxide/styrene oxide diblock copolymer E17S8 in aqueous solution.
2003-07-01
Quantitative analysis of modified proteins by LC-MS/MS of peptides labeled with phenyl isocyanate.
2003-06-20
Assessment of biotransformation of the arene moiety of styrene in volunteers and occupationally exposed workers.
2003-06-15
Models of neurotoxicity: extrapolation of benchmark doses in vitro.
2003-06
Asymmetric environments in encapsulation complexes.
2003-05-21
A facile solid-phase synthesis of substituted 2(5H)-furanones from polymer-supported alpha-selenocarboxylic acids.
2003-05-13
In vitro metabolism of styrene to styrene oxide in liver and lung of Cyp2E1 knockout mice.
2003-05-09
Construction of a bacterial biosensor for styrene.
2003-05-08
Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions.
2003-05-01
Biocatalysis of nitro substituted styrene oxides by non-conventional yeasts.
2003-05
Simultaneous direct electrochemiluminescence and catalytic voltammetry detection of DNA in ultrathin films.
2003-04-30
Effect of epoxide hydrolase and glutathione S-tranferase genotypes on the induction of micronuclei and DNA damage by styrene-7,8-oxide in vitro.
2003-04-20
Styrene-7,8-oxide activates a complex apoptotic response in neuronal PC12 cell line.
2003-03
The repair of DNA damage induced in human peripheral lymphocytes with styrene oxide.
2003
Genetic polymorphism of drug-metabolizing enzymes and styrene-induced DNA damage.
2003
Styrene-7,8-oxide.
2002
Patents

Patents

04108831
1
04372969
1
04416895
1
04536447
1
04585796
1
05171753
1
05637727
1
05658904
1
05719150
1
05750740
1
06603034
1
06784256
1
08299085
6
JP2000217597A
1
JP2001072996A
1
JP2003261571A
1
JP2006525402A
4
JP2011001287A
1
JPH00767669A
1
JPH01265053A
1
JPH06312988A
1
JPH0632867A
1
JPH07188634A
1
JPH0748582A
1
JPH08113558A
1
JPH09227472A
1
JPH0977756A
1
JPS57118A
1
JPS57159532A
1
JPS5718643A
1
JPS59189192A
1
JPS61176547A
1
JPS61268675A
1
JPS62174091A
1
JPS6245607A
1
Name Type Language
NSC-637
Preferred Name English
STYRENE OXIDE
HSDB  
Systematic Name English
STYRENE 7,8-OXIDE
Common Name English
BENZENE, (EPOXYETHYL)-
Systematic Name English
STYRENE-7,8-OXIDE [IARC]
Common Name English
ETHANE, 1,2-EPOXY-1-PHENYL-
Systematic Name English
STYRENE OXIDE [HSDB]
Common Name English
(±)-PHENYLOXIRANE
Systematic Name English
1,2-EPOXYETHYLBENZENE
Systematic Name English
STYRYL OXIDE
Systematic Name English
PHENETHYLENE OXIDE
Common Name English
OXIRANE, 2-PHENYL-
Systematic Name English
.ALPHA.,.BETA.-EPOXYSTYRENE
Systematic Name English
(±)-STYRENE OXIDE
Systematic Name English
NSC-7582
Code English
Classification Tree Code System Code
NCI_THESAURUS C45408
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
Code System Code Type Description
FDA UNII
9QH06NGT6O
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
CAS
96-09-3
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
HSDB
2646
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
NSC
637
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
CHEBI
17907
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
EPA CompTox
DTXSID2021286
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
WIKIPEDIA
Styrene-7,8-oxide
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
PUBCHEM
7276
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
NSC
7582
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
SMS_ID
300000053604
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
NCI_THESAURUS
C44447
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
ECHA (EC/EINECS)
202-476-7
Created by admin on Mon Mar 31 22:03:49 GMT 2025 , Edited by admin on Mon Mar 31 22:03:49 GMT 2025
PRIMARY
SUBSTANCE RECORD
Structure of STYRENE OXIDE
NIH
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