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Details

Stereochemistry ACHIRAL
Molecular Formula C25H23ClN2O7
Molecular Weight 498.912
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BINIFIBRATE

SMILES

CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OC(COC(=O)C2=CC=CN=C2)COC(=O)C3=CN=CC=C3

InChI

InChIKey=BFYRHDVAEJIBON-UHFFFAOYSA-N
InChI=1S/C25H23ClN2O7/c1-25(2,35-20-9-7-19(26)8-10-20)24(31)34-21(15-32-22(29)17-5-3-11-27-13-17)16-33-23(30)18-6-4-12-28-14-18/h3-14,21H,15-16H2,1-2H3

HIDE SMILES / InChI

Description

Binifibrate is an anti-arteriosclerotic and hypolipidaemic agent. It was used under the name Biniwas in patients with hyperlipidemia, however, it is currently withdrawn from the market.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8583
BINIWAS

Approved Use

Hyperlipidemia.
PubMed

PubMed

TitleDatePubMed
Biotransformation kinetic of binifibrate and identification of its metabolites.
1991-05
[Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].
1990-10
Microhaemorheological properties of binifibrate. Part I: Experimental studies.
1983
Microhaemorheological properties of binifibrate. Part II: Preliminary open studies in patients with peripheral arteriopathies.
1983

Sample Use Guides

In Vivo Use Guide
The recommended dose is 600 mg three times daily.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
BINIFIBRATE
INN   MART.   MI   WHO-DD  
INN  
Official Name English
BINIWAS
Preferred Name English
binifibrate [INN]
Common Name English
Binifibrate [WHO-DD]
Common Name English
BINIFIBRATE [MART.]
Common Name English
BINIFIBRATE [MI]
Common Name English
2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID ESTER WITH 1,3-DINICOTININOYLOXY-2-PROPANOL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C98150
Created by admin on Mon Mar 31 18:02:04 GMT 2025 , Edited by admin on Mon Mar 31 18:02:04 GMT 2025
Code System Code Type Description
PUBCHEM
68884
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PRIMARY
MERCK INDEX
m2498
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PRIMARY Merck Index
SMS_ID
100000085907
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PRIMARY
EPA CompTox
DTXSID80219113
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PRIMARY
ChEMBL
CHEMBL2106582
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PRIMARY
EVMPD
SUB05837MIG
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PRIMARY
CAS
69047-39-8
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PRIMARY
INN
4956
Created by admin on Mon Mar 31 18:02:04 GMT 2025 , Edited by admin on Mon Mar 31 18:02:04 GMT 2025
PRIMARY
DRUG CENTRAL
372
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PRIMARY
NCI_THESAURUS
C72991
Created by admin on Mon Mar 31 18:02:04 GMT 2025 , Edited by admin on Mon Mar 31 18:02:04 GMT 2025
PRIMARY
FDA UNII
9NGZ4GPE20
Created by admin on Mon Mar 31 18:02:04 GMT 2025 , Edited by admin on Mon Mar 31 18:02:04 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of BINIFIBRATE
NIH
NCATS
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