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Details

Stereochemistry ACHIRAL
Molecular Formula C25H23ClN2O7
Molecular Weight 498.912
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BINIFIBRATE

SMILES

CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OC(COC(=O)C2=CC=CN=C2)COC(=O)C3=CN=CC=C3

InChI

InChIKey=BFYRHDVAEJIBON-UHFFFAOYSA-N
InChI=1S/C25H23ClN2O7/c1-25(2,35-20-9-7-19(26)8-10-20)24(31)34-21(15-32-22(29)17-5-3-11-27-13-17)16-33-23(30)18-6-4-12-28-14-18/h3-14,21H,15-16H2,1-2H3

HIDE SMILES / InChI

Description

Binifibrate is an anti-arteriosclerotic and hypolipidaemic agent. It was used under the name Biniwas in patients with hyperlipidemia, however, it is currently withdrawn from the market.

CNS Activity

Originator

Target Info

Target Info

Primary TargetPharmacologyConditionPotency
Condition Info

Condition Info

ConditionModalityTargetsHighest PhaseProduct
Primary
BINIWAS
PMID

PMID

TitleDatePMID
Microhaemorheological properties of binifibrate. Part II: Preliminary open studies in patients with peripheral arteriopathies.
1983
Microhaemorheological properties of binifibrate. Part I: Experimental studies.
1983
[Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].
1990 Oct
Biotransformation kinetic of binifibrate and identification of its metabolites.
1991 May
Patent

Patent

Sample Use Guides

In Vivo Use Guide
The recommended dose is 600 mg three times daily.
Route of Administration: Oral
Name Type Language
BINIFIBRATE
INN   MART.   MI   WHO-DD  
INN  
Official Name English
BINIFIBRATE [INN]
Common Name English
BINIFIBRATE [WHO-DD]
Common Name English
BINIFIBRATE [MART.]
Common Name English
BINIFIBRATE [MI]
Common Name English
BINIWAS
Brand Name English
2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID ESTER WITH 1,3-DINICOTININOYLOXY-2-PROPANOL
Common Name English
Code System Code Type Description
PUBCHEM
68884
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY SWITZERF
MERCK INDEX
M2498
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY Merck Index
EPA CompTox
69047-39-8
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY
ChEMBL
CHEMBL2106582
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY
EVMPD
SUB05837MIG
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY
CAS
69047-39-8
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY
INN
4956
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY
NCI_THESAURUS
C72991
Created by admin on Tue Mar 06 11:24:57 UTC 2018 , Edited by admin on Tue Mar 06 11:24:57 UTC 2018
PRIMARY