U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C53H83NO14
Molecular Weight 958.2244
Optical Activity UNSPECIFIED
Defined Stereocenters 15 / 15
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EVEROLIMUS

SMILES

CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1OCCO

InChI

InChIKey=HKVAMNSJSFKALM-GKUWKFKPSA-N
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
EVEROLIMUS
DASH   EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
EVEROLIMUS [MART.]
Common Name English
RAD-666
Code English
SDZ RAD
Common Name English
EVEROLIMUS [ORANGE BOOK]
Common Name English
ZORTRESS
Brand Name English
RAD001
Code English
SDZ-RAD
Code English
EVEROLIMUS [INN]
Common Name English
CERTICAN
Brand Name English
AFINITOR
Brand Name English
EVEROLIMUS [USAN]
Common Name English
EVEROLIMUS [MI]
Common Name English
VOTUBIA
Brand Name English
RAD-001
Code English
EVEROLIMUS [JAN]
Common Name English
EVEROLIMUS [EMA EPAR]
Common Name English
RAD 666
Code English
40-O-(2-HYDROXYETHYL)-RAPAMYCIN
Common Name English
EVEROLIMUS [VANDF]
Common Name English
EVEROLIMUS [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-ATC L04AA18
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
WHO-VATC QL04AA18
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
EMA ASSESSMENT REPORTS VOTUBIA (AUTHORIZED: TUBEROUS SCLEROSIS)
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
NDF-RT N0000175605
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
EMA ASSESSMENT REPORTS AFINITOR (AUTHORIZED: CARCINOMA, RENAL CELL)
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
WHO-ATC L01XE10
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
EMA ASSESSMENT REPORTS AFINITOR (AUTHORIZED: PANCREATIC NEOPLASMS)
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
NDF-RT N0000175076
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
WHO-VATC QL01XE10
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
LIVERTOX 393
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
Code System Code Type Description
HSDB
159351-69-6
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
MERCK INDEX
M5220
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY Merck Index
ChEMBL
CHEMBL1908360
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
NDF-RT
N0000182141
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY Cytochrome P450 3A4 Inhibitors [MoA]
DRUG BANK
DB01590
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
INN
7863
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
CAS
159351-69-6
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
IUPHAR
5889
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
WIKIPEDIA
EVEROLIMUS
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
MESH
C107135
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
LactMed
159351-69-6
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
EPA CompTox
159351-69-6
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
PUBCHEM
6442177
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY SWITZERF
NDF-RT
N0000182137
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY Cytochrome P450 2D6 Inhibitors [MoA]
EVMPD
SUB02065MIG
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY
NDF-RT
N0000185503
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY P-Glycoprotein Inhibitors [MoA]
RXCUI
141704
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY RxNorm
NCI_THESAURUS
C48387
Created by admin on Tue Mar 06 11:15:54 UTC 2018 , Edited by admin on Tue Mar 06 11:15:54 UTC 2018
PRIMARY