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Details

Stereochemistry ACHIRAL
Molecular Formula C12H21N2O4P
Molecular Weight 288.2799
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIAZOXON

SMILES

CCOP(=O)(OCC)OC1=CC(C)=NC(=N1)C(C)C

InChI

InChIKey=VBLJFQYCTRKKKF-UHFFFAOYSA-N
InChI=1S/C12H21N2O4P/c1-6-16-19(15,17-7-2)18-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris).
2000 Aug
Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype.
2000 Jul
Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides.
2002 Sep 5
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.
2003 Feb
Paraoxonase 1 status in the Thai population.
2005
Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.
2005 Feb
Degradation and by-product formation of diazinon in water during UV and UV/H(2)O(2) treatment.
2006 Aug 25
Each lipase has a unique sensitivity profile for organophosphorus inhibitors.
2006 May
Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions.
2006 Sep
Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon.
2007 Jan
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds.
2009 Apr 15
Paraoxonase 1 (PON1) status and substrate hydrolysis.
2009 Feb 15
Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides.
2009 Jul 24
Engineering human PON1 in an E. coli expression system.
2010
Serum albumins and detoxication of anti-cholinesterase agents.
2010 Sep 6
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon.
2011 Mar
Environmental impact on vascular development predicted by high-throughput screening.
2011 Nov
Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides.
2012 Jan
Assessing protection against OP pesticides and nerve agents provided by wild-type HuPON1 purified from Trichoplusia ni larvae or induced via adenoviral infection.
2013 Mar 25
In vitro evaluation of neurotoxicity potential and oxidative stress responses of diazinon and its degradation products in rat brain synaptosomes.
2015 Feb 17
Name Type Language
DIAZOXON
Common Name English
DIAZINON OXYGEN ANALOG
Common Name English
PHOSPHORIC ACID, DIETHYL 6-METHYL-2-(1-METHYLETHYL)-4-PYRIMIDINYL ESTER
Common Name English
DIETHYL (6-METHYL-2-PROPAN-2-YLPYRIMIDIN-4-YL) PHOSPHATE
Systematic Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 657802
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID5037523
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
PRIMARY
CAS
962-58-3
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
PRIMARY
FDA UNII
9FX08D2L1U
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
PRIMARY
PUBCHEM
13754
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
PRIMARY
MESH
C000912
Created by admin on Fri Dec 15 18:22:47 GMT 2023 , Edited by admin on Fri Dec 15 18:22:47 GMT 2023
PRIMARY