DIAZOXON

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H21N2O4P
Molecular Weight	288.2799
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOP(=O)(OCC)OC1=CC(C)=NC(=N1)C(C)C

InChI

InChIKey=VBLJFQYCTRKKKF-UHFFFAOYSA-N

InChI=1S/C12H21N2O4P/c1-6-16-19(15,17-7-2)18-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C12H21N2O4P
Molecular Weight	288.2799
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
In vitro evaluation of neurotoxicity potential and oxidative stress responses of diazinon and its degradation products in rat brain synaptosomes.	2015-02-17	25562544
Assessing protection against OP pesticides and nerve agents provided by wild-type HuPON1 purified from Trichoplusia ni larvae or induced via adenoviral infection.	2013-03-25	23123254
Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides.	2012-01	21972196
Environmental impact on vascular development predicted by high-throughput screening.	2011-11	21788198
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon.	2011-03	20981111
Serum albumins and detoxication of anti-cholinesterase agents.	2010-09-06	20211614
Engineering human PON1 in an E. coli expression system.	2010	20221869
Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides.	2009-07-24	19446239
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds.	2009-04-15	19371602
Paraoxonase 1 (PON1) status and substrate hydrolysis.	2009-02-15	19071155
Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon.	2007-01	17018647
Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions.	2006-09	16978018
Degradation and by-product formation of diazinon in water during UV and UV/H(2)O(2) treatment.	2006-08-25	16436313
Each lipase has a unique sensitivity profile for organophosphorus inhibitors.	2006-05	16449251
Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.	2005-02	15525694
Paraoxonase 1 status in the Thai population.	2005	15924216
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.	2003-02	12563177
Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides.	2002-09-05	12243867
Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris).	2000-08	10871426
Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype.	2000-07	10898114

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:11:40 GMT 2025` Edited by `admin` on `Mon Mar 31 19:11:40 GMT 2025`
Record UNII	9FX08D2L1U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIAZINON OXYGEN ANALOG

Preferred Name

English

DIAZOXON

Common Name

English

PHOSPHORIC ACID, DIETHYL 6-METHYL-2-(1-METHYLETHYL)-4-PYRIMIDINYL ESTER

Common Name

English

DIETHYL (6-METHYL-2-PROPAN-2-YLPYRIMIDIN-4-YL) PHOSPHATE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

657802