DIAZOXON

CCOP(=O)(OCC)OC1=CC(C)=NC(=N1)C(C)C

InChIKey=VBLJFQYCTRKKKF-UHFFFAOYSA-N

InChI=1S/C12H21N2O4P/c1-6-16-19(15,17-7-2)18-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides.	2002 Sep 5	12243867
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.	2003 Feb	12563177
Paraoxonase 1 status in the Thai population.	2005	15924216
Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions.	2006 Sep	16978018
Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon.	2007 Jan	17018647
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds.	2009 Apr 15	19371602
Engineering human PON1 in an E. coli expression system.	2010	20221869
Serum albumins and detoxication of anti-cholinesterase agents.	2010 Sep 6	20211614
Environmental impact on vascular development predicted by high-throughput screening.	2011 Nov	21788198
Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides.	2012 Jan	21972196
Assessing protection against OP pesticides and nerve agents provided by wild-type HuPON1 purified from Trichoplusia ni larvae or induced via adenoviral infection.	2013 Mar 25	23123254
In vitro evaluation of neurotoxicity potential and oxidative stress responses of diazinon and its degradation products in rat brain synaptosomes.	2015 Feb 17	25562544

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:22:47 GMT 2023` Edited by `admin` on `Fri Dec 15 18:22:47 GMT 2023`
Record UNII	9FX08D2L1U
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DIAZOXON

Common Name

English

DIAZINON OXYGEN ANALOG

Common Name

English

PHOSPHORIC ACID, DIETHYL 6-METHYL-2-(1-METHYLETHYL)-4-PYRIMIDINYL ESTER

Common Name

English

DIETHYL (6-METHYL-2-PROPAN-2-YLPYRIMIDIN-4-YL) PHOSPHATE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

657802