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Details

Stereochemistry ACHIRAL
Molecular Formula C15H14O4.C4H11NO2
Molecular Weight 363.4049
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MENBUTONE DIOLAMINE

SMILES

OCCNCCO.COC1=CC=C(C(=O)CCC(O)=O)C2=CC=CC=C12

InChI

InChIKey=NYBYAEQEGMYBOZ-UHFFFAOYSA-N
InChI=1S/C15H14O4.C4H11NO2/c1-19-14-8-6-11(13(16)7-9-15(17)18)10-4-2-3-5-12(10)14;6-3-1-5-2-4-7/h2-6,8H,7,9H2,1H3,(H,17,18);5-7H,1-4H2

HIDE SMILES / InChI
Menbutone is a choleretic compound which is used in veterinary medicine at a dose rate up to 10 mg/kg bw by parenteral (intravenous or intramuscular) route in bovine, ovine, caprine, porcine, and equine species. Menbutone stimulates the digestive tract by increasing excretion of bile, gastric acid, and pancreatic juices by two to five times baseline. It is marketed for veterinary use in Europe under several brand names.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Genabil

Approved Use

Menbutone is only to be administered to a small number of animals or individual animals which are not intended for immediate slaughter. The total daily intake should be at most 3.6 mg per person of 60 kg bw per day, resulting from the ADI of 0.06 mg/kg bw/day.

Launch Date

1996
PubMed

PubMed

TitleDatePubMed
Elimination and distribution of menbutone (Genabil) in rats.
1969
The choleretic effect of menbutone and clanobutin sodium in steers.
1982 May 1
Patents

Sample Use Guides

Menbutone is used in veterinary medicine at doses up to 10 mg/kg bw delivered by intravenous and intramuscular injection to bovine, ovine, caprine, porcine and equine species.
Route of Administration: Other
In Vitro Use Guide
Unknown
Name Type Language
MENBUTONE DIOLAMINE
Common Name English
GENABIL
Brand Name English
ETHANOL, 2,2'-IMINOBIS-, 4-METHOXY-.GAMMA.-OXO-1-NAPHTHALENEBUTANOATE (SALT)
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID10225343
Created by admin on Sat Dec 16 07:14:20 GMT 2023 , Edited by admin on Sat Dec 16 07:14:20 GMT 2023
PRIMARY
FDA UNII
9F80J3GMVF
Created by admin on Sat Dec 16 07:14:20 GMT 2023 , Edited by admin on Sat Dec 16 07:14:20 GMT 2023
PRIMARY
CAS
74332-55-1
Created by admin on Sat Dec 16 07:14:20 GMT 2023 , Edited by admin on Sat Dec 16 07:14:20 GMT 2023
PRIMARY
PUBCHEM
71587270
Created by admin on Sat Dec 16 07:14:20 GMT 2023 , Edited by admin on Sat Dec 16 07:14:20 GMT 2023
PRIMARY