FENHARMANE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	UNKNOWN
Molecular Formula	C18H18N2
Molecular Weight	262.3489
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENHARMANE

Structure Search

SMILES

C(C1NCCC2=C1NC3=C2C=CC=C3)C4=CC=CC=C4

InChI

InChIKey=LHVNPTMRAQQPID-UHFFFAOYSA-N

InChI=1S/C18H18N2/c1-2-6-13(7-3-1)12-17-18-15(10-11-19-17)14-8-4-5-9-16(14)20-18/h1-9,17,19-20H,10-12H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5612958 | https://www.ncbi.nlm.nih.gov/pubmed/14477998 | https://www.europsy-journal.com/article/S0924-9338(00)94202-0/pdf

FENHARMANE, a reserpine-like substance, is a neuroleptic developed and clinically tested in the Czech Republic.

CNS Activity

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Nialamid and its combinations with reserpine-like substances (fenoharman, reserpine) in the therapy of endogenous depressions].	1962 Jul 5	14477998
The action of chlorpromazine and amitriptyline on the effects of phenoharmane.	1967 Nov	5612958

Sample Use Guides

In Vivo Use Guide

Oral LD50 1200 mg/kg. Intravenous LD50 37 mg/kg.

Route of Administration: Other

Name

Type

Language

FENHARMANE

Official Name

English

NSC-172131

Code

English

1-BENZYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOLE

Systematic Name

English

fenharmane [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197

Created by admin on Sat Dec 16 18:04:03 GMT 2023 , Edited by admin on Sat Dec 16 18:04:03 GMT 2023

Code System Code Type Description

CAS

3851-30-7

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EVMPD

SUB07564MIG

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ChEMBL

CHEMBL2106159

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EPA CompTox

DTXSID101043296

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PUBCHEM

71167

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INN

1780

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FDA UNII

9E96TNX6EZ

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NSC

172131

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NCI_THESAURUS

C65650

Created by admin on Sat Dec 16 18:04:03 GMT 2023 , Edited by admin on Sat Dec 16 18:04:03 GMT 2023

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SMS_ID

100000081275

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ACTIVE MOIETY


					9E96TNX6EZ