PRIDINOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H25NO
Molecular Weight	295.4186
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRIDINOL

Structure Search

SMILES

OC(CCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=RQXCLMGKHJWMOA-UHFFFAOYSA-N

InChI=1S/C20H25NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1-2,4-7,10-13,22H,3,8-9,14-17H2

HIDE SMILES / InChI

Description
Sources: http://www.mims.com/india/drug/info/pridinol?type=full&mtype=generic | https://www.ncbi.nlm.nih.gov/pubmed/12935797 | http://mmpharm1.tradekorea.com/product/detail/P260632/Skeletal-Muscle-Relaxants.html?minisiteprodgroupno=29432

Pridinol mesilate is a centrally acting muscle relaxant that is used in the symptomatic treatment of muscle spasm. It is also used as the hydrochloride salt for its antimuscarinic activity in the management of parkinsonism.

CNS Activity

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?D08418 \| https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+2684 \| https://www.ncbi.nlm.nih.gov/pubmed/8102927	Antagonist 2778

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Muscle spasm 40 Sources: http://mmpharm1.tradekorea.com/product/detail/P260632/Skeletal-Muscle-Relaxants.html?minisiteprodgroupno=29432 https://www.ncbi.nlm.nih.gov/pubmed/12935797	Primary		Approved 8429	Pridinol Approved Use Muscle spasms

PubMed

PubMed

Title	Date	PubMed
Development and validation of a dissolution test for meloxicam and pridinol mesylate from combined tablet formulation.	2010 Mar	20838523
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	2011 Jul 14	21599003

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Oral Muscle spasms Adult: As mesilate: Usual initial: 2-8 mg tid; Maintenance: 4-8 mg daily.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

PRIDINOL

Official Name

English

PRIDINOL [HSDB]

Common Name

English

C-238

Code

English

Pridinol [WHO-DD]

Common Name

English

NSC-23016

Code

English

PRIDINOL [MI]

Common Name

English

pridinol [INN]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QM03BX03

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

WHO-ATC

M03BX03

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

NCI_THESAURUS

C29710

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C73319

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PRIMARY

INN

1320

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PUBCHEM

4904

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CAS

511-45-5

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NSC

23016

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RXCUI

34479

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RxNorm

ECHA (EC/EINECS)

208-128-0

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ChEMBL

CHEMBL404215

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FDA UNII

9E75Q6SUUB

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SMS_ID

100000081633

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MERCK INDEX

m9129

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Merck Index

CHEBI

75247

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WIKIPEDIA

PRIDINOL

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

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MESH

C009185

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EPA CompTox

DTXSID0045090

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

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DRUG CENTRAL

2263

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EVMPD

SUB10037MIG

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DRUG BANK

DB13642

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HSDB

2684

Created by admin on Fri Dec 15 16:11:24 GMT 2023 , Edited by admin on Fri Dec 15 16:11:24 GMT 2023

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ACTIVE MOIETY


					9E75Q6SUUB

PRIDINOL

SALT/SOLVATE (PARENT)


					AQ4K0AJT6G

PRIDINOL MESILATE

SALT/SOLVATE (PARENT)


					3HI2Q2Y868

PRIDINOL HYDROCHLORIDE