| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H7INO3.Na |
| Molecular Weight | 331.0527 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[O-]C(=O)CNC(=O)C1=CC=CC=C1[131I]
InChI
InChIKey=XYITYKDGJLHYPW-UDYUCQKZSA-M
InChI=1S/C9H8INO3.Na/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;/h1-4H,5H2,(H,11,14)(H,12,13);/q;+1/p-1/i10+4;
IODOHIPPURIC ACID I-131 (ortho-Iodohippuric Acid I-131, [I-123]-OIH) is an iodine-containing compound used in pyelography as a radiopaque medium. Iodine-123 labelled ortho-Iodohippuric acid was used in the early 1970's as a kidney imaging agent or tracer that "lights-up" inside your body when scanned, but over the years its use has declined. [I-123]-OIH is primarily extracted by the renal tubules and has excellent pharmacokinetic properties, with a clearance only slightly less than that of p-aminohippuran, but its use has been compromised by the suboptimal imaging characteristics of the 364-keV photon of 131I and the delivery of relatively high radiation doses to kidneys and thyroid in patients with impaired renal function
Approval Year
PubMed
Patents
Sample Use Guides
After the coinjection of approximately 74 MBq (;2 mCi) of 99mTc(CO)3(NTA) and approximately 11.1 MBq (300 mCi) of 131I-OIH, imaging was performed for 24 min using an Infinia camera (GE Healthcare) with a 9.5-mm (3/8-in) crystal fitted with a high-energy collimator
Route of Administration:
Intravenous
ACTIVE MOIETY
SUBSTANCE RECORD
