Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.5567 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChIKey=KIQFUORWRVZTHT-OPTMKGCMSA-N
InChI=1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-16,18-21H,4-14H2,1-3H3,(H,26,27)/t15-,16-,18+,19-,20+,21+,23+,24-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry. | 2008-02 |
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| Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells. | 2007-10 |
|
| Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase. | 2007-09 |
|
| In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007-01 |
|
| Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). | 2005-09-30 |
|
| Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts. | 2005-07 |
|
| Novel pathways of bile acid metabolism involving CYP3A4. | 2005-02-21 |
|
| Specificity of human alcohol dehydrogenase 1C*2 (gamma2gamma2) for steroids and simulation of the uncompetitive inhibition of ethanol metabolism. | 2003-02-01 |
|
| Vitamin D receptor as an intestinal bile acid sensor. | 2002-05-17 |
|
| The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. | 2001-03-13 |
|
| St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. | 2000-06-20 |
Patents
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| Code System | Code | Type | Description | ||
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5283906
Created by
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17639
Created by
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96JBM35FXF
Created by
admin on Mon Mar 31 19:14:10 GMT 2025 , Edited by admin on Mon Mar 31 19:14:10 GMT 2025
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1553-56-6
Created by
admin on Mon Mar 31 19:14:10 GMT 2025 , Edited by admin on Mon Mar 31 19:14:10 GMT 2025
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DTXSID60935182
Created by
admin on Mon Mar 31 19:14:10 GMT 2025 , Edited by admin on Mon Mar 31 19:14:10 GMT 2025
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PRIMARY |
PARENT (METABOLITE)
SUBSTANCE RECORD
