Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.5567 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O
InChI
InChIKey=KIQFUORWRVZTHT-OPTMKGCMSA-N
InChI=1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-16,18-21H,4-14H2,1-3H3,(H,26,27)/t15-,16-,18+,19-,20+,21+,23+,24-/m1/s1
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.5567 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. | 2000 Jun 20 |
|
| The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. | 2001 Mar 13 |
|
| Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts. | 2005 Jul |
|
| Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). | 2005 Sep 30 |
|
| In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 Jan |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:30:32 UTC 2023
by
admin
on
Fri Dec 15 18:30:32 UTC 2023
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| Record UNII |
96JBM35FXF
|
| Record Status |
Validated (UNII)
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| Record Version |
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17639
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96JBM35FXF
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1553-56-6
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DTXSID60935182
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