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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25NO2.ClH
Molecular Weight 347.879
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FOMOCAINE HYDROCHLORIDE

SMILES

Cl.C(CN1CCOCC1)CC2=CC=C(COC3=CC=CC=C3)C=C2

InChI

InChIKey=HWDXMCUKRADNLV-UHFFFAOYSA-N
InChI=1S/C20H25NO2.ClH/c1-2-6-20(7-3-1)23-17-19-10-8-18(9-11-19)5-4-12-21-13-15-22-16-14-21;/h1-3,6-11H,4-5,12-17H2;1H

HIDE SMILES / InChI
Fomocaine is a local anesthetic used in the gel formulations for the relief of pain associated with burns and wounds. Fomocaine blocks both sodium and calcium voltage-gated ion cahnnel currents.

Originator

Sources: www.drugfuture.com/chemdata/fomocaine.html

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
100.0 µM [Ki]
Conditions
PubMed

PubMed

TitleDatePubMed
Effects and toxicity of new fomocaine derivatives and of 2-hydroxypropyl-beta-cyclodextrin inclusion compounds in rats.
2004
In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats.
2006
A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part 1.
2007
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Transdermal
In Vitro Use Guide
Unknown
Name Type Language
FOMOCAINE HYDROCHLORIDE
WHO-DD  
Common Name English
MORPHOLINE, 4-(3-(4-(PHENOXYMETHYL)PHENYL)PROPYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
MORPHOLINE, 4-(3-(4-(PHENOXYMETHYL)PHENYL)PROPYL)-, HYDROCHLORIDE
Systematic Name English
Fomocaine hydrochloride [WHO-DD]
Common Name English
Code System Code Type Description
PUBCHEM
171527
Created by admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
PRIMARY
EPA CompTox
DTXSID80205137
Created by admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
PRIMARY
CAS
56583-43-8
Created by admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
PRIMARY
FDA UNII
96285SEX30
Created by admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
PRIMARY