Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H25NO2.ClH |
| Molecular Weight | 347.879 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.C(CN1CCOCC1)CC2=CC=C(COC3=CC=CC=C3)C=C2
InChI
InChIKey=HWDXMCUKRADNLV-UHFFFAOYSA-N
InChI=1S/C20H25NO2.ClH/c1-2-6-20(7-3-1)23-17-19-10-8-18(9-11-19)5-4-12-21-13-15-22-16-14-21;/h1-3,6-11H,4-5,12-17H2;1H
| Molecular Formula | C20H25NO2 |
| Molecular Weight | 311.418 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Local anaesthetic effectivity and toxicity of fomocaine, five N-free fomocaine metabolites and two chiralic fomocaine derivatives in rats compared with procaine. | 2001 |
|
| [Synthesis and pharmacologic action of chiral fomocaine ((4-[2-methyl-3-(morpholin-4-yl)propyl)benzyl)-phenyl-ether and (4-(1-methyl-3-(morpholin-4-yl)propyl]benzyl)-phenyl-ether). 13. Synthesis of new compounds with local anesthetic action]. | 2001 Aug |
|
| [[Physical chemical, pharmacological and toxicologic properties of fomocaine metabolites] ]. | 2001 Jan |
|
| Local anaesthetic effects and toxicity of seven new diethanolamine and morpholine derivatives of fomocaine. Testing in rats compared with procaine and tetracaine. | 2003 |
|
| In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats. | 2006 |
|
| [In vitro investigations of phase I metabolism of the fomocaine derivative Oe 9000 with pig liver homogenates]. | 2006 Nov |
|
| A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part III. | 2007 |
|
| A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II. | 2007 |
|
| Blockade of TTX-resistant and TTX-sensitive Na+ currents in cultured dorsal root ganglion neurons by fomocaine and the fomocaine derivative Oe 9000. | 2010 Oct 28 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:33:36 GMT 2023
by
admin
on
Sat Dec 16 08:33:36 GMT 2023
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| Record UNII |
96285SEX30
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID80205137
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56583-43-8
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admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
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96285SEX30
Created by
admin on Sat Dec 16 08:33:36 GMT 2023 , Edited by admin on Sat Dec 16 08:33:36 GMT 2023
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ACTIVE MOIETY |