Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8HF15O2 |
| Molecular Weight | 414.0684 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI
InChIKey=SNGREZUHAYWORS-UHFFFAOYSA-N
InChI=1S/C8HF15O2/c9-2(10,1(24)25)3(11,12)4(13,14)5(15,16)6(17,18)7(19,20)8(21,22)23/h(H,24,25)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Perfluorooctanoic acid has persistent effects on peroxisome proliferation and related parameters in mouse liver. | 1992 Winter |
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| Comparison of the elimination between perfluorinated fatty acids with different carbon chain length in rats. | 2001 Apr 16 |
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| Nature of the liquid crystalline phase transitions in the cesium pentadecafluorooctanoate (CsPFO)-water system: the nematic-to-isotropic transition. | 2001 May |
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| Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid. | 2001 May 15 |
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| Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice. | 2001 Oct 15 |
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| Characterization of the adipose tissue atrophy induced by peroxisome proliferators in mice. | 2002 Feb |
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| Monitoring perfluorinated surfactants in biota and surface water samples following an accidental release of fire-fighting foam into Etobicoke Creek. | 2002 Feb 15 |
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| Interhelical packing in detergent micelles. Folding of a cystic fibrosis transmembrane conductance regulator construct. | 2002 Feb 22 |
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| Rapid determination of underivatized pyroglutamic acid, glutamic acid, glutamine and other relevant amino acids in fermentation media by LC-MS-MS. | 2002 Jan |
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| Peroxisome proliferator-activated receptor agonists inhibit inflammatory edema and hyperalgesia. | 2002 Jun |
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| Perfluorooctanesulfonate and related fluorinated hydrocarbons in mink and river otters from the United States. | 2002 Jun 15 |
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| A comparative study of commercial liquid chromatographic detectors for the analysis of underivatized amino acids. | 2002 Jun 28 |
|
| Functional activation of peroxisome proliferator-activated receptor alpha (PPARalpha) by environmental chemicals in relation to their toxicities. | 2002 Nov |
|
| Toxicity of ammonium perfluorooctanoate in male cynomolgus monkeys after oral dosing for 6 months. | 2002 Sep |
|
| Oligomerization of a peptide derived from the transmembrane region of the sodium pump gamma subunit: effect of the pathological mutation G41R. | 2002 Sep 20 |
|
| Impact of perfluorooctanoic acid on the structure of the zooplankton community in indoor microcosms. | 2003 Feb 12 |
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| Binding of perfluorooctanoic acid to rat and human plasma proteins. | 2003 Jun |
|
| Concerns over common perfluorinated surfactant. | 2003 Jun 1 |
|
| Study of the interactions between lysozyme and a fully-fluorinated surfactant in aqueous solution at different surfactant-protein ratios. | 2003 Nov |
|
| Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in vacuum cleaner dust collected in Japanese homes. | 2003 Oct |
|
| Mortality of employees of a perfluorooctanesulphonyl fluoride manufacturing facility. | 2003 Oct |
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| The relationship between liver peroxisome proliferation and adipose tissue atrophy induced by peroxisome proliferator exposure and withdrawal in mice. | 2003 Sep 1 |
|
| An occupational exposure assessment of a perfluorooctanesulfonyl fluoride production site: biomonitoring. | 2003 Sep-Oct |
|
| Perfluorooctane sulfonate--a quite mobile anionic anthropogenic surfactant, ubiquitously found in the environment. | 2004 |
|
| Impact of perfluorooctanoic acid on fathead minnow (Pimephales promelas) fatty acyl-CoA oxidase activity, circulating steroids, and reproduction in outdoor microcosms. | 2004 Aug |
|
| Detection of perfluorooctane surfactants in Great Lakes water. | 2004 Aug 1 |
|
| Perfluorinated compounds in coastal waters of Hong Kong, South China, and Korea. | 2004 Aug 1 |
|
| Pharmacokinetics of perfluorooctanoate in cynomolgus monkeys. | 2004 Dec |
|
| Enhanced potential for oxidative stress in livers of senescent rats by the peroxisome proliferator-activated receptor alpha agonist perfluorooctanoic acid. | 2004 Jan |
|
| Anomalous dielectric relaxation of water molecules at the surface of an aqueous micelle. | 2004 Jan 22 |
|
| Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. | 2004 Jul 1 |
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| The developmental toxicity of perfluoroalkyl acids and their derivatives. | 2004 Jul 15 |
|
| Homogeneous liquid-liquid extraction of uranium(VI) using tri-n-octylphosphine oxide. | 2004 Jun |
|
| Characterization of risk for general population exposure to perfluorooctanoate. | 2004 Jun |
|
| Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver. | 2004 Jun 1 |
|
| Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids. | 2004 Jun 15 |
|
| Perfluorinated sources outside and inside. | 2004 Mar 1 |
|
| The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat. | 2004 Mar 1 |
|
| Hazards of fast food. | 2004 May |
|
| Binding of perfluorooctanoic acid to rat liver-form and kidney-form alpha2u-globulins. | 2004 Nov |
|
| Mesomorphous structure and properties of non-equimolar complexes of poly(ethylenimine) and perfluorooctanoic acid. | 2004 Nov 23 |
|
| Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. | 2004 Oct 1 |
|
| Analytical techniques and method validation for the measurement of selected semivolatile and nonvolatile organofluorochemicals in air. | 2004 Sep |
|
| Determination of perfluorooctane sulfonate and perfluorooctanoic acid in human plasma by large volume injection capillary column switching liquid chromatography coupled to electrospray ionization mass spectrometry. | 2004 Sep |
|
| Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries. | 2004 Sep 1 |
Patents
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| Code System | Code | Type | Description | ||
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947VD76D3L
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35549
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335-67-1
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DTXSID8031865
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7137
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m8542
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C023036
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PERFLUOROOCTANOIC ACID
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206-397-9
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9554
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95114
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
