Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8HF15O2 |
| Molecular Weight | 414.0684 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI
InChIKey=SNGREZUHAYWORS-UHFFFAOYSA-N
InChI=1S/C8HF15O2/c9-2(10,1(24)25)3(11,12)4(13,14)5(15,16)6(17,18)7(19,20)8(21,22)23/h(H,24,25)
| Molecular Formula | C8HF15O2 |
| Molecular Weight | 414.0684 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacokinetics of perfluorooctanoate in cynomolgus monkeys. | 2004-12 |
|
| Mesomorphous structure and properties of non-equimolar complexes of poly(ethylenimine) and perfluorooctanoic acid. | 2004-11-23 |
|
| Binding of perfluorooctanoic acid to rat liver-form and kidney-form alpha2u-globulins. | 2004-11 |
|
| Mitochondrial permeability transition as the critical target of N-acetyl perfluorooctane sulfonamide toxicity in vitro. | 2004-11 |
|
| Determination of perfluorooctane sulfonate, perfluorooctanoate and perfluorooctane sulfonylamide in human plasma by column-switching liquid chromatography-electrospray mass spectrometry coupled with solid-phase extraction. | 2004-10-15 |
|
| Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. | 2004-10-01 |
|
| Structural micellar transition for fluorinated and hydrogenated sodium carboxylates induced by solubilization of benzyl alcohol. | 2004-09-28 |
|
| Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries. | 2004-09-01 |
|
| Analytical techniques and method validation for the measurement of selected semivolatile and nonvolatile organofluorochemicals in air. | 2004-09 |
|
| Determination of perfluorooctane sulfonate and perfluorooctanoic acid in human plasma by large volume injection capillary column switching liquid chromatography coupled to electrospray ionization mass spectrometry. | 2004-09 |
|
| Toxicity of perfluorooctane sulfonic acid and perfluorooctanoic acid to Chironomus tentans. | 2004-09 |
|
| The toxicology of perfluorooctanoate. | 2004-08-27 |
|
| Detection of perfluorooctane surfactants in Great Lakes water. | 2004-08-01 |
|
| Perfluorinated compounds in coastal waters of Hong Kong, South China, and Korea. | 2004-08-01 |
|
| Impact of perfluorooctanoic acid on fathead minnow (Pimephales promelas) fatty acyl-CoA oxidase activity, circulating steroids, and reproduction in outdoor microcosms. | 2004-08 |
|
| Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy. | 2004-08 |
|
| The developmental toxicity of perfluoroalkyl acids and their derivatives. | 2004-07-15 |
|
| Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. | 2004-07-01 |
|
| Gas-phase NMR technique for studying the thermolysis of materials: thermal decomposition of ammonium perfluorooctanoate. | 2004-07-01 |
|
| [Status of perfluorochemicals in adult serum and umbilical blood in Shenyang]. | 2004-07 |
|
| 19F Magnetic resonance imaging of perfluorooctanoic acid encapsulated in liposome for biodistribution measurement. | 2004-07 |
|
| Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids. | 2004-06-15 |
|
| Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver. | 2004-06-01 |
|
| Homogeneous liquid-liquid extraction of uranium(VI) using tri-n-octylphosphine oxide. | 2004-06 |
|
| A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians. | 2004-06 |
|
| Characterization of risk for general population exposure to perfluorooctanoate. | 2004-06 |
|
| Fluorotelomer alcohol biodegradation yields poly- and perfluorinated acids. | 2004-05-15 |
|
| Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. | 2004-05-07 |
|
| Hazards of fast food. | 2004-05 |
|
| Effects of perfluorooctane sulfonate and perfluorooctanoic acid on the zooplanktonic community. | 2004-05 |
|
| Perfluorinated sources outside and inside. | 2004-03-01 |
|
| The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat. | 2004-03-01 |
|
| The influence of time, sex and geographic factors on levels of perfluorooctane sulfonate and perfluorooctanoate in human serum over the last 25 years. | 2004-03 |
|
| Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington. | 2004-03 |
|
| Peroxisomal enzymes and 8-hydroxydeoxyguanosine in rat liver treated with perfluorooctanoic acid. | 2004-02-06 |
|
| Biotransformation of N-ethyl perfluorooctanesulfonamide by rainbow trout (Onchorhynchus mykiss) liver microsomes. | 2004-02-01 |
|
| Predicting the biodegradation products of perfluorinated chemicals using CATABOL. | 2004-02 |
|
| Anomalous dielectric relaxation of water molecules at the surface of an aqueous micelle. | 2004-01-22 |
|
| Identification of long-chain perfluorinated acids in biota from the Canadian Arctic. | 2004-01-15 |
|
| Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan. | 2004-01 |
|
| Enhanced potential for oxidative stress in livers of senescent rats by the peroxisome proliferator-activated receptor alpha agonist perfluorooctanoic acid. | 2004-01 |
|
| Perfluorooctane sulfonate--a quite mobile anionic anthropogenic surfactant, ubiquitously found in the environment. | 2004 |
|
| Another fast-food fear. | 2003-12 |
|
| Perfluorooctanesulfonate and other fluorochemicals in the serum of American Red Cross adult blood donors. | 2003-12 |
|
| Study of the interactions between lysozyme and a fully-fluorinated surfactant in aqueous solution at different surfactant-protein ratios. | 2003-11 |
|
| An occupational exposure assessment of a perfluorooctanesulfonyl fluoride production site: biomonitoring. | 2003-10-03 |
|
| Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in vacuum cleaner dust collected in Japanese homes. | 2003-10 |
|
| Mortality of employees of a perfluorooctanesulphonyl fluoride manufacturing facility. | 2003-10 |
|
| The relationship between liver peroxisome proliferation and adipose tissue atrophy induced by peroxisome proliferator exposure and withdrawal in mice. | 2003-09-01 |
|
| The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid. | 1992-09-22 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:51:07 GMT 2025
by
admin
on
Mon Mar 31 18:51:07 GMT 2025
|
| Record UNII |
947VD76D3L
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
947VD76D3L
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
35549
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
335-67-1
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
300000053523
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
DTXSID8031865
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
7137
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
m8542
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | Merck Index | ||
|
C023036
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
PERFLUOROOCTANOIC ACID
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
206-397-9
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
9554
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY | |||
|
95114
Created by
admin on Mon Mar 31 18:51:07 GMT 2025 , Edited by admin on Mon Mar 31 18:51:07 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT | |||
|
TARGET -> INHIBITOR |
Ki
|
||
|
|
SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
