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Details

Stereochemistry ACHIRAL
Molecular Formula C8HF15O2
Molecular Weight 414.0684
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PERFLUOROOCTANOIC ACID

SMILES

OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI

InChIKey=SNGREZUHAYWORS-UHFFFAOYSA-N
InChI=1S/C8HF15O2/c9-2(10,1(24)25)3(11,12)4(13,14)5(15,16)6(17,18)7(19,20)8(21,22)23/h(H,24,25)

HIDE SMILES / InChI

Molecular Formula C8HF15O2
Molecular Weight 414.0684
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid.
1992 Sep 22
Perfluorooctanoic acid has persistent effects on peroxisome proliferation and related parameters in mouse liver.
1992 Winter
trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.
1999 Dec 1
Perfluorooctanoic acid, a peroxisome-proliferating hypolipidemic agent, dissociates apolipoprotein B48 from lipoprotein particles and decreases secretion of very low density lipoproteins by cultured rat hepatocytes.
1999 Mar 25
Hypophysectomy and/or peroxisome proliferators strongly influence the levels of phase II xenobiotic metabolizing enzymes in rat testis.
1999 Sep 30
Analysis of the native quaternary structure of vanilloid receptor 1.
2001 Jul 27
Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid.
2001 May 15
Quantitative characterization of trace levels of PFOS and PFOA in the Tennessee River.
2002 Apr 15
Perfluorooctanesulfonate and related fluorinated hydrocarbons in marine mammals, fishes, and birds from coasts of the Baltic and the Mediterranean Seas.
2002 Aug 1
Solubilization of polycyclic aromatic hydrocarbons by perfluorinated surfactant micelles.
2002 Jan
Peroxisome proliferator-activated receptor agonists inhibit inflammatory edema and hyperalgesia.
2002 Jun
Perfluorooctanesulfonate and related fluorinated hydrocarbons in mink and river otters from the United States.
2002 Jun 15
Occurrence and persistence of perfluorooctanesulfonate and other perfluorinated surfactants in groundwater at a fire-training area at Wurtsmith Air Force Base, Michigan, USA.
2003 Apr
Impact of perfluorooctanoic acid on the structure of the zooplankton community in indoor microcosms.
2003 Feb 12
Epidemiologic assessment of worker serum perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations and medical surveillance examinations.
2003 Mar
Human donor liver and serum concentrations of perfluorooctanesulfonate and other perfluorochemicals.
2003 Mar 1
The relationship between liver peroxisome proliferation and adipose tissue atrophy induced by peroxisome proliferator exposure and withdrawal in mice.
2003 Sep 1
An occupational exposure assessment of a perfluorooctanesulfonyl fluoride production site: biomonitoring.
2003 Sep-Oct
Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy.
2004 Aug
Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan.
2004 Jan
[Status of perfluorochemicals in adult serum and umbilical blood in Shenyang].
2004 Jul
Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk.
2004 Jul 1
A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians.
2004 Jun
Fluorotelomer alcohol biodegradation yields poly- and perfluorinated acids.
2004 May 15
Binding of perfluorooctanoic acid to rat liver-form and kidney-form alpha2u-globulins.
2004 Nov
Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries.
2004 Sep 1
Structural micellar transition for fluorinated and hydrogenated sodium carboxylates induced by solubilization of benzyl alcohol.
2004 Sep 28
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:44:00 GMT 2023
Edited
by admin
on Fri Dec 15 17:44:00 GMT 2023
Record UNII
947VD76D3L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PERFLUOROOCTANOIC ACID
HSDB   MI  
Systematic Name English
OCTANOIC ACID, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-PENTADECAFLUORO
Common Name English
OCTANOIC ACID, PENTADECAFLUORO
Common Name English
PERFLUOROHEPTANECARBOXYLIC ACID
Systematic Name English
PENTADECAFLUOROOCTANOIC ACID
Systematic Name English
NSC-95114
Code English
PERFLUOROOCTANOIC ACID [MI]
Common Name English
PERFLUROOCTANOIC-ACID
Common Name English
PFOA
Common Name English
PERFLUORO-1-HEPTANECARBOXYLIC ACID
Systematic Name English
PERFLUOROOCTANOIC ACID [IARC]
Common Name English
N-PERFLUOROOCTANOIC ACID
Common Name English
PERFLUOROOCTANOIC ACID [HSDB]
Common Name English
Code System Code Type Description
FDA UNII
947VD76D3L
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
CHEBI
35549
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
CAS
335-67-1
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
EPA CompTox
DTXSID8031865
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
HSDB
7137
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
MERCK INDEX
m8542
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY Merck Index
MESH
C023036
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
WIKIPEDIA
PERFLUOROOCTANOIC ACID
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
ECHA (EC/EINECS)
206-397-9
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
PUBCHEM
9554
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
NSC
95114
Created by admin on Fri Dec 15 17:44:00 GMT 2023 , Edited by admin on Fri Dec 15 17:44:00 GMT 2023
PRIMARY
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