Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C39H45N2O6 |
| Molecular Weight | 637.7844 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
COC1=CC=C2C[C@@H]3C4=C(OC5=CC=C(C[C@@H]6N(C)CCC7=C6C=C(OC1=C2)C(OC)=C7)C=C5)C(OC)=C(OC)C=C4CC[N+]3(C)C
InChI
InChIKey=GMAJRXOYQVZSRJ-IOWSJCHKSA-N
InChI=1S/C39H45N2O6/c1-40-16-14-26-21-33(43-5)35-23-29(26)30(40)18-24-8-11-28(12-9-24)46-39-37-27(22-36(44-6)38(39)45-7)15-17-41(2,3)31(37)19-25-10-13-32(42-4)34(20-25)47-35/h8-13,20-23,30-31H,14-19H2,1-7H3/q+1/t30-,31+/m0/s1
Dimethyltubocurarine (metocurine) is a non-depolarizing muscle relaxant. It binds to muscle acetylcholine receptor by bridging the to alpha and non-alpha subunits from the ligand binding site. Dimethyltubocurarine was used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
Approval Year
Sample Use Guides
Dimethyl-tubocurarine iodide is administered intravenously in isotonic sodium chloride solution for muscle relaxtion in surgery. The average initial dose is approximately 2 mg (80 units) and is injected slowly over a period of one to one
and one-half minutes.
Route of Administration:
Intravenous
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WHO-ATC |
M03AA04
Created by
admin on Sat Dec 16 18:56:14 GMT 2023 , Edited by admin on Sat Dec 16 18:56:14 GMT 2023
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WHO-VATC |
QM03AA04
Created by
admin on Sat Dec 16 18:56:14 GMT 2023 , Edited by admin on Sat Dec 16 18:56:14 GMT 2023
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35-67-6
Created by
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947TXZ810I
Created by
admin on Sat Dec 16 18:56:14 GMT 2023 , Edited by admin on Sat Dec 16 18:56:14 GMT 2023
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CHEMBL1259
Created by
admin on Sat Dec 16 18:56:14 GMT 2023 , Edited by admin on Sat Dec 16 18:56:14 GMT 2023
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24892848
Created by
admin on Sat Dec 16 18:56:14 GMT 2023 , Edited by admin on Sat Dec 16 18:56:14 GMT 2023
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PRIMARY |
SALT/SOLVATE (PARENT)
SUBSTANCE RECORD
