U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.HO4P.2H2O
Molecular Weight 177.9894
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM PHOSPHATE, DIBASIC, DIHYDRATE

SMILES

O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

InChIKey=KDQPSPMLNJTZAL-UHFFFAOYSA-L
InChI=1S/2Na.H3O4P.2H2O/c;;1-5(2,3)4;;/h;;(H3,1,2,3,4);2*1H2/q2*+1;;;/p-2

HIDE SMILES / InChI

Description

Phosphoric acid, also known as orthophosphoric acid, is used in dentistry and orthodontics to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed. In addition, this acid is a part of product ProcalAmine, which is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition. In combination with dextrose (glucose) and levulose (fructose), phosphoric acid relieves nausea due to upset stomach from intestinal flu, stomach flu, and food or drink indiscretions. In addition, homeopathic product, Brain power contains also phosphoric acid and this product is used to temporarily relieve symptoms of general physical weakness and listlessness, including: fatigue; sore muscles & joints; dry skin; absence of sexual desire; occasional sleeplessness.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8429
PROCALAMINE

Approved Use

ProcalAmine is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition.

Launch Date

1982
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Primary
Approved
8429
SODIUM PHOSPHATES INJECTION

Approved Use

Sodium Phosphates Injection, USP, 3mM P/mL, is indicated as a source of phosphorus, for addition to large volume intravenous fluids, to prevent or correct hypophosphatemia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. The concomitant amount of sodium (4 mEq/mL) must be calculated into total electrolyte content of such prepared solutions.
PubMed

PubMed

TitleDatePubMed
Diurnal variation in the levels of glucose and related substances in healthy and diabetic subjects during starvation.
1967 Feb
Determination of inorganic phosphate in serum and saliva using a synthetic receptor.
2003 Jun 12
Amperometric biosensor for determining human salivary phosphate.
2005 Aug 15
Phosphorus amendment reduces hepatic and renal oxidative stress in mallards ingesting lead-contaminated sediments.
2006 Jun
Patents

Patents

04224407
30
04355158
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04487752
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04533660
37
04537718
27
04565680
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04613463
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04744965
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05917041
35
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05962694
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05994368
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06017919
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07517894
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29
08415349
29
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29
08436024
27
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27
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27
08497397
28
08501732
37
08524751
27
08524909
29
08536197
29
08546588
29
08569341
29
08586204
27
08591943
28
08609675
28
08618094
28
08629144
28
08633216
27
08658117
27
08674111
28
08674141
28
08680120
29
08703784
27
08709615
27
08791139
28
08841467
27
08846746
27
20020025910
30
20030003160
27
20120070359
27
20140171390
27
2600813
27
US3382035
27

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
SODIUM PHOSPHATE DIBASIC DIHYDRATE
WHO-DD  
Preferred Name English
SODIUM PHOSPHATE, DIBASIC, DIHYDRATE
II  
Common Name English
Sodium phosphate dibasic dihydrate [WHO-DD]
Common Name English
DISODIUM PHOSPHATE DIHYDRATE [EP MONOGRAPH]
Common Name English
SODIUM PHOSPHATE, DIBASIC, DIHYDRATE [II]
Common Name English
PHOSPHORIC ACID, DISODIUM SALT, DIHYDRATE
Common Name English
DISODIUM PHOSPHATE DIHYDRATE
EP  
Systematic Name English
SODIUM PHOSPHATE, DIBASIC DIHYDRATE
MI  
Common Name English
SODIUM PHOSPHATE, DIBASIC DIHYDRATE [MI]
Common Name English
DISODIUM HYDROGEN PHOSPHATE, DIHYDRATE
Systematic Name English
DISODIUM PHOSPHATE, DIHYDRATE
Systematic Name English
DISODIUM HYDROGEN PHOSPHATE DIHYDRATE
Systematic Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 76415
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
NCI_THESAURUS C29730
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
Code System Code Type Description
DRUG BANK
DBSALT001974
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
FDA UNII
94255I6E2T
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
DAILYMED
94255I6E2T
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
PUBCHEM
6451167
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
RXCUI
1311323
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY RxNorm
EPA CompTox
DTXSID1074250
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
CAS
10028-24-7
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
NCI_THESAURUS
C66547
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
SMS_ID
100000076104
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
MERCK INDEX
m10059
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY Merck Index
EVMPD
SUB11921MIG
Created by admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
PRIMARY
NIH
NCATS
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ACCESSIBILITY
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