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US Approved Rx

27

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Primary Target

Leishmania infantum

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Approved

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Approval Year

1921

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Unknown

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Fatigue

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Hyperphosphatemia

27

Hypophosphatemia

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Lose body protein

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Nausea

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Diagnostic

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Palliative

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Chemical

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FDA UNII

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EPA CompTox

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Electrolyte solutions

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Osmotically acting laxatives

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Salts, Hydrates, Esters, etc.

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Showing 1 - 10 of 31 results

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Phosphate ion

NK08V8K8HR

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

NITROETHANE

6KEL3ZAU0V

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

METHYL PYRROLE-2-CARBOXYLATE

3BEG2CK3LU

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Tributyltin Chloride

CA82T4QR5F

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

p-Nitroaniline

1MRQ0QZG7G

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Leishmania infantum

Conditions:

P-nitroaniline is a chromogenic molecule that is used as a dyestuff intermediate in industrial applications. In biochemical research, enzyme assays utilize modified aminoacyl or peptidyl p-nitroanilines as substrates. The enzyme catalyzes the release...

of free p-nitroaniline, which is the basis of the colorimetric determination of the enzyme activity. Applications of the colorimetric properties of p-nitroanilide include the design of biopolymer drug delivery systems and of solid supports for enzyme immobilization. A kinetic analysis of the α-chymotrypsin catalyzed hydrolysis of aminoacyl and peptidyl p-nitroanilide substrates in vesicles has been reported. It has been shown to possess anti-leishmanial activity.

Phosphoric Acid

E4GA8884NN

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

AMMONIUM SODIUM PHOSPHATE TETRAHYDRATE

K78U8WLV4H

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

PHOSPHATE ION(2-)

33UE6C4909

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

AMMONIUM PHOSPHATE, TRIBASIC

2ZJF06M0I9

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

AMMONIUM SODIUM PHOSPHATE

SWP615T2VF

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Status:

US Approved Rx (1981)

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Hypophosphatemia

Sore muscles & joints

Lose body protein

Occasional sleeplessness

Hypophosphatemia

Hyperphosphatemia

Phosphate is a major intracellular anion in mammals. Hydrogen phopshate is a protonated form of phosphate. In serum, phosphate exists in two forms, dihydrogen phosphate (H2PO4) and its salt, mono-hydrogen phosphate (HPO4). At the physiologic pH of 7....

40, the pK of H2PO4 is 6.8 and the ratio of HPO4 to H2PO4 is 4:1. Altered level of phosphate can be an indicator of various disorders, such as chronic renal failure, hypoparathyroidism, familial intermittent hyperphosphatemia, endocrine disorders, hyperthyroidism, acromegaly, juvenile hypogonadism, etc. These disorders may lead to either hyper- or hypophosphatemia, which can be caused by cellular shifts of phosphate. Patients with hypophosphatemia can be treated with dietary phosphate supplements (potassium phosphate, for example).

Showing 1 - 10 of 31 results

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