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Details

Stereochemistry EPIMERIC
Molecular Formula C12H14N2O3.C10H16O4S
Molecular Weight 466.548
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPROQUALONE CAMSILATE

SMILES

CC1(C)[C@@H]2CC[C@@]1(CS(O)(=O)=O)C(=O)C2.CC3=NC4=C(C=CC=C4)C(=O)N3CC(O)CO

InChI

InChIKey=AJNMCFBQWSXQHS-STOWLHSFSA-N
InChI=1S/C12H14N2O3.C10H16O4S/c1-8-13-11-5-3-2-4-10(11)12(17)14(8)6-9(16)7-15;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-5,9,15-16H,6-7H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t;7-,10-/m.1/s1

HIDE SMILES / InChI
Diproqualone was used primarily for the treatment of inflammatory pain associated with osteoarthritis. The analgesic activity of diproqualoneis synergistic with that of noramidopyrine. It also display anti-inflammatory action in the rat, inhibiting plantar edema with dextran or serotonin, atopic edema from ovalbumin, etc. It has spasmolytic, anticholinergic and antihistaminic action in higher doses. It is not hypnotic and has no anticonvulsant effects. The therapeutic symptoms for diproqualone are all types of pain: postoperative, posttraumatic, dental, neuritis, anti-inflammatory arthritis, etc.

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation.
2010-05
Name Type Language
DIPROQUALONE CAMSILATE
WHO-DD  
Common Name English
4(3H)-QUINAZOLINONE, 3-(2,3-DIHYDROXYPROPYL)-2-METHYL-, MONO((1S)-7,7-DIMETHYL-2-OXOBICYCLO(2.2.1)HEPTANE-1-METHANESULFONATE) (SALT)
Preferred Name English
BICYCLO(2.2.1)HEPTANE-1-METHANESULFONIC ACID, 7,7-DIMETHYL-2-OXO-, (1S)-, COMPD. WITH 3-(2,3-DIHYDROXYPROPYL)-2-METHYL-4(3H)-QUINAZOLINONE (1:1)
Systematic Name English
Diproqualone camsilate [WHO-DD]
Common Name English
Code System Code Type Description
FDA UNII
92QYQ513QO
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
PRIMARY
SMS_ID
100000087537
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
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PUBCHEM
118984423
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
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EPA CompTox
DTXSID70980345
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
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CAS
63768-21-8
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
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EVMPD
SUB01792MIG
Created by admin on Mon Mar 31 21:46:07 GMT 2025 , Edited by admin on Mon Mar 31 21:46:07 GMT 2025
PRIMARY