DOMOPREDNATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H36O5
Molecular Weight	428.561
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CCC[C@]4(OC(=O)CCC)C(C)=O

InChI

InChIKey=IYBYNRHXGXDDDS-VRRJBYJJSA-N

InChI=1S/C26H36O5/c1-5-7-22(30)31-26(16(2)27)12-6-8-20-19-10-9-17-14-18(28)11-13-24(17,3)23(19)21(29)15-25(20,26)4/h11,13-14,19-21,23,29H,5-10,12,15H2,1-4H3/t19-,20-,21-,23+,24-,25-,26-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3653463 | https://www.ncbi.nlm.nih.gov/pubmed/3888709 | Morton, I.K., Hall, J.M. (2012) Concise Dictionary of Pharmacological Agents, page 104, retrieved from: https://books.google.ru/books?id=tsjrCAAAQBAJ

Domoprednate is a corticosteroid, a glucocorticoid, with anti-inflammatory and anti-allergic properties. Domoprednate is inferior to betamethasone valerate in the same category of dermatoses and equally well tolerated. It can be characterized as a medium-active corticosteroid. Domoprednate can be used topically in the treatment of skin disorders, such as eczema, psoriasis and atopic dermatitis.

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

The 0.1% ointment was applied twice daily for 4 weeks.

Route of Administration: Topical

Name

Type

Language

DOMOPREDNATE

Official Name

English

11.BETA.,17A-DIHYDROXY-D-HOMOPREGNA-1,4-DIENE-3,20-DIONE 17A-BUTYRATE

Common Name

English

domoprednate [INN]

Common Name

English

RO 12-7024

Code

English

DOMOPREDNATE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521