TESICAM

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H11ClN2O3
Molecular Weight	314.723
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(NC(=O)C2C(=O)NC(=O)C3=CC=CC=C23)C=C1

InChI

InChIKey=HWCORKBTTGTRDY-UHFFFAOYSA-N

InChI=1S/C16H11ClN2O3/c17-9-5-7-10(8-6-9)18-15(21)13-11-3-1-2-4-12(11)14(20)19-16(13)22/h1-8,13H,(H,18,21)(H,19,20,22)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10991837 | https://www.ncbi.nlm.nih.gov/pubmed/4976043

Tesicam is a dioxoisoquinoline derivative patented by Pfizer, Chas. and Co., Inc. as an anti-inflammatory agent. In preclinical models, Tesicam shows potent anti-inflammatory activity against carrageenin-induced edema in rats.

Originator

Approval Year

PubMed

Title	Date	PubMed
Dioxoisoquinoline-4-carboxanilides--a new class of non-steroidal anti-inflammatory agents.	1969-04-19	4976043

Patents

Name

Type

Language

CP-13,608

Preferred Name

English

TESICAM

Official Name

English

CP-13608

Code

English

4-ISOQUINOLINECARBOXAMIDE, N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1,3-DIOXO-

Systematic Name

English

tesicam [INN]

Common Name

English

NSC-355083

Code

English

TESICAM [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257