CARBARSONE

First approved in 1944

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9AsN2O4
Molecular Weight	260.079
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)NC1=CC=C(C=C1)[As](O)(O)=O

InChI

InChIKey=WWXBHTZSYYGCSG-UHFFFAOYSA-N

InChI=1S/C7H9AsN2O4/c9-7(11)10-6-3-1-5(2-4-6)8(12,13)14/h1-4H,(H3,9,10,11)(H2,12,13,14)

HIDE SMILES / InChI

Description
Sources: http://www.centerforfoodsafety.org/files/20130930_docket-fda-2009-p-0594_signed-arsenic-cp-response_94793.pdf

Carbarsone is an antiambeic, antihistomonal drug effective in controlling and preventing blackhead disease in turkeys (a disease caused by a protozoan parasite Histomonas meleagridis). Carbarsone was approved by FDA, however, it has not been marketed in the USA scince 1996.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Blackhead disease 1 Sources: http://www.centerforfoodsafety.org/files/20130930_docket-fda-2009-p-0594_signed-arsenic-cp-response_94793.pdf	Preventing		Approved 8583	CARB-O-SEP Approved Use Aid in the prevention of blackhead in turkeys.

PubMed

Title	Date	PubMed
Current treatment options for Dientamoeba fragilis infections.	2012-12	24533282
Virulence Of Entamoeba Histolytica According To The Strains In Korea: III. Amebicial Response Of Antiamoebic Agents On Several Strains Of Entamoeba Histolytica In Vitro.	1969-12	12913525
Trichomonas urethritis in males.	1955-12	13270111
Balantidial dysentery.	1953-09	13082481
Less commonly recognized clinical features of amebiasis.	1952-04	14925826
The mechanism of coprosterol formation in vivo: 2. Its inhibition by succinyl sulphathiazole and by carbarsone.	1943	16747699

Patents

Sample Use Guides

In Vivo Use Guide

227 to 340.5 (0.025 to 0.0375 percent) grams per ton feed.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

NSC-32868

Preferred Name

English

CARBARSONE

Official Name

English

AMEBAN

Common Name

English

carbarsone [INN]

Common Name

English

CARBARSONE [GREEN BOOK]

Common Name

English

CARBARSON

Common Name

English

CARBARSONE [MART.]

Common Name

English

Carbarsone [WHO-DD]

Common Name

English

N-Carbamoylarsanilic acid

Common Name

English

ARSONIC ACID, (4-((AMINOCARBONYL)AMINO)PHENYL)-

Common Name

English

CARBARSONE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C277