Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C69H134O6 |
| Molecular Weight | 1059.7987 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCCCCCC
InChI
InChIKey=DMBUODUULYCPAK-UHFFFAOYSA-N
InChI=1S/C69H134O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-55-58-61-67(70)73-64-66(75-69(72)63-60-57-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)65-74-68(71)62-59-56-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h66H,4-65H2,1-3H3
Tribehenin is composed of glycerin and behenic acid, a naturally-occurring long-chain fatty acid. Tribehenin is found in animal and vegetable fats and oils such as tallow, palm-nut and coconut oils. It is used as a conditioning agent in a wide variety of skin care products, including makeup formulas, creams and lotions, sunscreen products, and skin care and skin cleansing products. Tribehenin is considered a low hazard ingredient by the Cosmetics Database, which notes that it can be a penetration enhancer and assist other chemicals in reaching lower levels of the skin.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Preparation and characterization of solid lipid nanoparticles containing cyclosporine by the emulsification-diffusion method. | 2010-09-07 |
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| Non-destructive methods of characterization of risperidone solid lipid nanoparticles. | 2010-09 |
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| Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010-07 |
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| Effects of lubricants on binary direct compression mixtures. | 2010-04 |
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| Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. | 2010-03-10 |
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| Box-Behnken experimental design in the development of pectin-compritol ATO 888 compression coated colon targeted drug delivery of mesalamine. | 2010-03 |
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| Innovation of novel sustained release compression-coated tablets for lornoxicam: formulation and in vitro investigations. | 2010-03 |
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| Carbamazepine-loaded porous microspheres for short-term sustained drug delivery. | 2010-01 |
|
| Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. | 2010-01 |
|
| Encapsulation of ethylhexyl methoxycinnamate, a light-sensitive UV filter, in lipid nanoparticles. | 2010 |
|
| Glycerol monolaurate and dodecylglycerol effects on Staphylococcus aureus and toxic shock syndrome toxin-1 in vitro and in vivo. | 2009-10-19 |
|
| An oral controlled release system for ambroxol hydrochloride containing a wax and a water insoluble polymer. | 2009-08-13 |
|
| The effect of geometric shape on the release properties of metronidazole from lipid matrix tablets. | 2009-08 |
|
| In vitro controlled release of colon targeted mesalamine from compritol ATO 888 based matrix tablets using factorial design. | 2009-07 |
|
| Solid lipid nanoparticles: a modern formulation approach in drug delivery system. | 2009-07 |
|
| Co-loading of a photostabilizer with the sunscreen agent, butyl methoxydibenzoylmethane in solid lipid microparticles. | 2009-02 |
|
| Entrapment and release of saquinavir using novel cationic solid lipid nanoparticles. | 2009-01-05 |
|
| Controlled-release carbamazepine matrix granules and tablets comprising lipophilic and hydrophilic components. | 2009-01 |
|
| Incorporation in lipid microparticles of the UVA filter, butyl methoxydibenzoylmethane combined with the UVB filter, octocrylene: effect on photostability. | 2009 |
|
| Mechanistic evaluation of the effect of sintering on Compritol 888 ATO matrices. | 2009 |
|
| Preparation and evaluation of miconazole nitrate-loaded solid lipid nanoparticles for topical delivery. | 2009 |
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| Diazepam-loaded solid lipid nanoparticles: design and characterization. | 2009 |
|
| Microsphere-based once-daily modified release matrix tablets for oral administration in angina pectoris. | 2008-06 |
|
| Solid lipid microparticles for the stability enhancement of the polar drug N6-cyclopentyladenosine. | 2008-05-01 |
|
| Hexagonal boron nitride as a tablet lubricant and a comparison with conventional lubricants. | 2008-04-02 |
|
| Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. | 2008-02-04 |
|
| [Preliminary study on brain-targeted drug delivery via inner ear]. | 2007-10 |
|
| In-vitro/in-vivo correlation of pulsatile drug release from press-coated tablet formulations: a pharmacoscintigraphic study in the beagle dog. | 2007-09 |
|
| Development of a new solid lipid nanoparticle formulation containing retinoic acid for topical treatment of acne. | 2007-08 |
|
| Solid lipid microparticles containing the sunscreen agent, octyl-dimethylaminobenzoate: effect of the vehicle. | 2007-06 |
|
| Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy. | 2007-05-24 |
|
| [Microstructure of novel solid lipid nanoparticle loaded triptolide]. | 2007-04 |
|
| Employment of cationic solid-lipid nanoparticles as RNA carriers. | 2007-01-27 |
|
| In vitro release--in vivo microbiological and toxicological studies on ketoconazole lipid granules. | 2007 |
|
| SLN as a topical delivery system for Artemisia arborescens essential oil: in vitro antiviral activity and skin permeation study. | 2007 |
|
| Enhanced retention of celecoxib-loaded solid lipid nanoparticles after intra-articular administration. | 2007 |
|
| Lymphatic uptake of lipid nanoparticles following endotracheal administration. | 2006-12 |
|
| In vitro controlled release of sodium ferulate from Compritol 888 ATO-based matrix tablets. | 2006-11-06 |
|
| In vitro and in vivo evaluation of floating riboflavin pellets developed using the melt pelletization process. | 2006-10-12 |
|
| Development and in vitro evaluation of a novel floating multiple unit dosage form obtained by melt pelletization. | 2006-09-28 |
|
| Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC. | 2006-06 |
|
| Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands. | 2006-02 |
|
| Study of formulation variables influencing the drug release rate from matrix tablets by experimental design. | 2006-01 |
|
| Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. | 2005-12-10 |
|
| [Effect of particle size on oral absorption of silymarin-loaded solid lipid nanoparticles]. | 2005-11 |
|
| Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy. | 2005-11 |
|
| Adaptation and optimization of the emulsification-diffusion technique to prepare lipidic nanospheres. | 2005-10 |
|
| SLN and NLC for topical delivery of ketoconazole. | 2005-08 |
|
| Solid lipid microparticles (SLM) containing juniper oil as anti-acne topical carriers: preliminary studies. | 2005 |
|
| Evaluation of hexagonal boron nitride as a new tablet lubricant. | 2005 |
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NCI_THESAURUS |
C83486
Created by
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8OC9U7TQZ0
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8OC9U7TQZ0
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1426386
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SUB20799
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62726
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18641-57-1
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DTXSID40171900
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100000086723
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242-471-7
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C78765
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SUBSTANCE RECORD
