Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C69H134O6 |
| Molecular Weight | 1059.7987 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCCCCCC
InChI
InChIKey=DMBUODUULYCPAK-UHFFFAOYSA-N
InChI=1S/C69H134O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-55-58-61-67(70)73-64-66(75-69(72)63-60-57-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)65-74-68(71)62-59-56-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h66H,4-65H2,1-3H3
| Molecular Formula | C69H134O6 |
| Molecular Weight | 1059.7987 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Tribehenin is composed of glycerin and behenic acid, a naturally-occurring long-chain fatty acid. Tribehenin is found in animal and vegetable fats and oils such as tallow, palm-nut and coconut oils. It is used as a conditioning agent in a wide variety of skin care products, including makeup formulas, creams and lotions, sunscreen products, and skin care and skin cleansing products. Tribehenin is considered a low hazard ingredient by the Cosmetics Database, which notes that it can be a penetration enhancer and assist other chemicals in reaching lower levels of the skin.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Comparative study of the lubricant performance of Compritol 888 ATO either used by blending or by hot melt coating. | 2003 Aug 27 |
|
| Physical and thermal characterisation of Precirol and Compritol as lipophilic glycerides used for the preparation of controlled-release matrix pellets. | 2003 Jul 9 |
|
| Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy. | 2004 Mar 5 |
|
| Solid lipid microparticles (SLM) containing juniper oil as anti-acne topical carriers: preliminary studies. | 2005 |
|
| Evaluation of hexagonal boron nitride as a new tablet lubricant. | 2005 |
|
| Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy. | 2005 Nov |
|
| Lymphatic uptake of lipid nanoparticles following endotracheal administration. | 2006 Dec |
|
| Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands. | 2006 Feb |
|
| Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC. | 2006 Jun |
|
| Development and in vitro evaluation of a novel floating multiple unit dosage form obtained by melt pelletization. | 2006 Sep 28 |
|
| Solid lipid microparticles containing the sunscreen agent, octyl-dimethylaminobenzoate: effect of the vehicle. | 2007 Jun |
|
| Employment of cationic solid-lipid nanoparticles as RNA carriers. | 2007 Mar-Apr |
|
| Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy. | 2007 May 24 |
|
| [Preliminary study on brain-targeted drug delivery via inner ear]. | 2007 Oct |
|
| In-vitro/in-vivo correlation of pulsatile drug release from press-coated tablet formulations: a pharmacoscintigraphic study in the beagle dog. | 2007 Sep |
|
| Incorporation in lipid microparticles of the UVA filter, butyl methoxydibenzoylmethane combined with the UVB filter, octocrylene: effect on photostability. | 2009 |
|
| Mechanistic evaluation of the effect of sintering on Compritol 888 ATO matrices. | 2009 |
|
| Preparation and evaluation of miconazole nitrate-loaded solid lipid nanoparticles for topical delivery. | 2009 |
|
| Diazepam-loaded solid lipid nanoparticles: design and characterization. | 2009 |
|
| Co-loading of a photostabilizer with the sunscreen agent, butyl methoxydibenzoylmethane in solid lipid microparticles. | 2009 Feb |
|
| Controlled-release carbamazepine matrix granules and tablets comprising lipophilic and hydrophilic components. | 2009 Jan |
|
| Entrapment and release of saquinavir using novel cationic solid lipid nanoparticles. | 2009 Jan 5 |
|
| In vitro controlled release of colon targeted mesalamine from compritol ATO 888 based matrix tablets using factorial design. | 2009 Jul |
|
| Solid lipid nanoparticles: a modern formulation approach in drug delivery system. | 2009 Jul |
|
| Glycerol monolaurate and dodecylglycerol effects on Staphylococcus aureus and toxic shock syndrome toxin-1 in vitro and in vivo. | 2009 Oct 19 |
|
| Encapsulation of ethylhexyl methoxycinnamate, a light-sensitive UV filter, in lipid nanoparticles. | 2010 |
|
| Effects of lubricants on binary direct compression mixtures. | 2010 Apr |
|
| Carbamazepine-loaded porous microspheres for short-term sustained drug delivery. | 2010 Jan |
|
| An oral controlled release system for ambroxol hydrochloride containing a wax and a water insoluble polymer. | 2010 Jan-Feb |
|
| Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 Jul |
|
| Box-Behnken experimental design in the development of pectin-compritol ATO 888 compression coated colon targeted drug delivery of mesalamine. | 2010 Mar |
|
| Non-destructive methods of characterization of risperidone solid lipid nanoparticles. | 2010 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 20:12:51 UTC 2023
by
admin
on
Sat Dec 16 20:12:51 UTC 2023
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| Record UNII |
8OC9U7TQZ0
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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C83486
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8OC9U7TQZ0
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1426386
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SUB20799
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62726
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18641-57-1
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DTXSID40171900
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100000086723
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242-471-7
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C78765
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