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Details

Stereochemistry RACEMIC
Molecular Formula C26H27ClN2
Molecular Weight 402.959
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CLOCINIZINE

SMILES

ClC1=CC=C(C=C1)C(N2CCN(C\C=C\C3=CC=CC=C3)CC2)C4=CC=CC=C4

InChI

InChIKey=ZSQANMZWGKYDER-JXMROGBWSA-N
InChI=1S/C26H27ClN2/c27-25-15-13-24(14-16-25)26(23-11-5-2-6-12-23)29-20-18-28(19-21-29)17-7-10-22-8-3-1-4-9-22/h1-16,26H,17-21H2/b10-7+

HIDE SMILES / InChI

Description

Clocinizine is an antihistamine derivative of diphenylmethylpiperazine. Clocinizine is a competitive and reversible H1 receptor antagonist. The drug is marketed in Spain under tradename Senioral in combination with phenylpropanolamine for temporary relief of nasal congestion in colds, rhinitis, and sinusitis.

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
Antagonist
2849
Name Type Language
CLOCINIZINE
INN   MI   WHO-DD  
INN  
Official Name English
CHLORCINNARIZINE
Preferred Name English
PIPERAZINE, 1-((4-CHLOROPHENYL) PHENYLMETHYL)-4-(3-PHENYL-2-PROPEN-1-YL)-
Common Name English
clocinizine [INN]
Common Name English
Clocinizine [WHO-DD]
Common Name English
CLIOCINIZINE
Common Name English
CLOCINIZINE [MI]
Common Name English
CHLOROCINNARIZINE
Common Name English
1-(P-CHLORO-.ALPHA.-PHENYLBENZYL)-4-CINNAMYLPIPERAZINE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C77435
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
FDA UNII
8HQJ711KH8
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
EVMPD
SUB06685MIG
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
ChEMBL
CHEMBL2104069
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
DRUG CENTRAL
688
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
EPA CompTox
DTXSID601027146
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
WIKIPEDIA
Clocinizine
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
CAS
298-55-5
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
PUBCHEM
5375618
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
INN
1599
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
MERCK INDEX
m3632
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY Merck Index
SMS_ID
100000084305
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY
RXCUI
402583
Created by admin on Mon Mar 31 18:22:52 GMT 2025 , Edited by admin on Mon Mar 31 18:22:52 GMT 2025
PRIMARY RxNorm
ACTIVE MOIETY
Structure of CLOCINIZINE
SALT/SOLVATE (PARENT)
Structure of CLOCINIZINE HYDROCHLORIDE
NIH
NCATS
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