CLOPERIDONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23ClN4O2
Molecular Weight	398.886
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=CC(=C1)N2CCN(CCCN3C(=O)NC4=C(C=CC=C4)C3=O)CC2

InChI

InChIKey=FXZJKVODWNYPKK-UHFFFAOYSA-N

InChI=1S/C21H23ClN4O2/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28/h1-3,5-8,15H,4,9-14H2,(H,23,28)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5885076

Cloperidone is a quinazolinedione derivative with sedative and antihypertensive properties. Cloperidone was discovered in 1965 by Miles Laboratories. The activity of the compound was demonstrated by behavioral observations in dogs and cats, by rotarod and activity cage experiments in mice and in other models.

Approval Year

PubMed

Title	Date	PubMed
New sedative and hypotensive 3-substituted 2,4(1H,3H)-quinazolinediones.	1965 Nov	5885076

Name

Type

Language

CLOPERIDONE

Official Name

English

Cloperidone [WHO-DD]

Common Name

English

3-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-2,4-(1H,3H)-QUINAZOLINEDIONE

Systematic Name

English

2,4(1H,3H)-QUINAZOLINEDIONE, 3-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-

Systematic Name

English

cloperidone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756