METHOSERPIDINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H40N2O9
Molecular Weight	608.6787
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12C[C@@H](OC(=O)C3=CC(OC)=C(OC)C(OC)=C3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]4([H])N(CCC5=C4NC6=C5C=C(OC)C=C6)C2

InChI

InChIKey=ULBNWNUHGJLQHO-VKMIBBQISA-N

InChI=1S/C33H40N2O9/c1-38-19-7-8-23-22(14-19)20-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)21(18)15-24(35)29(20)34-23/h7-8,11-12,14,18,21,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,21+,24-,27-,28+,31+/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14337851 | https://www.ncbi.nlm.nih.gov/pubmed/13715544

Methoserpidine is a synthetic isomer of reserpine, used in the 1960s as an antihypertensive drug. Initially, it was reported to be free from CNS side effects of reserpine (mild suppression of alertness, and mental depression). However, later clinical experience has shown that in a significant proportion of patients administration of the drug lead to episodes of depression.

Approval Year

PubMed

Title	Date	PubMed

Name

Type

Language

METHOSERPIDINE

Official Name

English

methoserpidine [INN]

Common Name

English

R-694

Code

English

RESERTENE

Brand Name

English

(-)-10-METHOXYDESERPIDINE

Common Name

English

3.BETA.,20.ALPHA.-YOHIMBAN-16.BETA.-CARBOXYLIC ACID, 18.BETA.-HYDROXY-10,17.ALPHA.-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE (ESTER)

Common Name

English

DESERPIDINE 10-METHOXYDESERPIDINE

Common Name

English

YOHIMBAN-16-CARBOXYLIC ACID, 10,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)-, METHYL ESTER, (3.BETA.,16.BETA.,17.ALPHA.,18.BETA.,20.ALPHA.)-

Common Name

English

R 694

Code

English

DECASERPIN

Common Name

English

DESERPIDINE, 10-METHOXY-

Common Name

English

10-MD

Common Name

English

DECASERPINE

Common Name

English

DECASERPIL

Common Name

English

DECASERPYL

Common Name

English

NSC-169423

Code

English

NEOSERPIN

Brand Name

English

DECOSERPYL

Common Name

English

10-METHOXYDESERPIDINE

Common Name

English

MINORAN

Brand Name

English

DEASERPYL

Common Name

English

Methoserpidine [WHO-DD]

Common Name

English

DESERPIDINE 10-METHOXYDESERPIDINE [MI]

Common Name

English

TENSERPINA

Common Name

English

METHOSERPIDINE [MART.]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QC02LA04