Details
Stereochemistry | ACHIRAL |
Molecular Formula | C9H14O |
Molecular Weight | 138.2069 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)=CC(=O)C=C(C)C
InChI
InChIKey=MTZWHHIREPJPTG-UHFFFAOYSA-N
InChI=1S/C9H14O/c1-7(2)5-9(10)6-8(3)4/h5-6H,1-4H3
Approval Year
PubMed
Title | Date | PubMed |
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Phorone (diisopropylidene acetone), a glutathione depletor, decreases rat glucocorticoid receptor binding in vivo. | 1992 Jul |
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Differential activation of heat-shock and oxidation-specific stress genes in chemically induced oxidative stress. | 1995 Jul 15 |
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Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers. | 1995 Mar 30 |
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Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes. | 2001 Apr |
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Role of glutathione in metabolic degradation of dichloromethane in rats. | 2002 Mar 24 |
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The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress. | 2005 Apr 1 |
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Phosphorinanes as ligands for palladium-catalyzed cross-coupling chemistry. | 2006 Jan 5 |
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Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice. | 2006 Jul |
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Serum iron increases with acute induction of hepatic heme oxygenase-1 in mice. | 2007 |
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Identification of glutathione depletion-responsive genes using phorone-treated rat liver. | 2007 Dec |
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Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue. | 2007 Jan |
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Decolorization potential of mixed microbial consortia for reactive and disperse textile dyestuffs. | 2007 Jun |
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High hepatic glutathione stores alleviate Fas-induced apoptosis in mice. | 2007 May |
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Comparison of the effects of buthioninesulfoximine and phorone on the metabolism of sulfur-containing amino acids in rat liver. | 2008 Apr 18 |
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Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats. | 2008 Sep |
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The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. | 2009 Jul 29 |
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Toxicogenomic biomarkers for liver toxicity. | 2009 Mar |
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Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation. | 2009 Mar |
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Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-kappaB. | 2010 Aug 1 |
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c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. | 2010 Jul |
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Mechanism-based biomarker gene sets for glutathione depletion-related hepatotoxicity in rats. | 2010 Sep 15 |
Patents
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Code System | Code | Type | Description | ||
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DTXSID1021584
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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PHORONE
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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207-986-3
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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504-20-1
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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10438
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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8F20OEI0MV
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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m8715
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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PRIMARY | Merck Index | ||
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C018637
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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35572
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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38718
Created by
admin on Sat Dec 16 02:15:50 GMT 2023 , Edited by admin on Sat Dec 16 02:15:50 GMT 2023
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PRIMARY |
SUBSTANCE RECORD