Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H12N2 |
| Molecular Weight | 208.2585 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C2C=CC3=CC=C(C)N=C3C2=N1
InChI
InChIKey=IYRGXJIJGHOCFS-UHFFFAOYSA-N
InChI=1S/C14H12N2/c1-9-3-5-11-7-8-12-6-4-10(2)16-14(12)13(11)15-9/h3-8H,1-2H3
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0006954 |
|||
Target ID: CHEMBL274 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22957890 |
67.0 µM [EC50] | ||
Target ID: CHEMBL2413 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22957890 |
1.6 µM [EC50] |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status. | 2011-02-01 |
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| Magneto-structural studies on heterobimetallic malonate-bridged M(II)Re(IV) complexes (M = Mn, Co, Ni and Cu). | 2010-12-21 |
|
| Bis(2,9-dimethyl-1,10-phenanthrolin-1-ium) hydrogen (S,S)-tartrate nona-hydrate. | 2010-12-11 |
|
| Aqua-(2,9-dimethyl-1,10-phenanthroline-κN,N')(formato-κO,O')(formato-κO)cobalt(II) monohydrate. | 2010-12-04 |
|
| Oxygen gas sensing by luminescence quenching in crystals of Cu(xantphos)(phen)+ complexes. | 2010-10-13 |
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| DNA binding, cytotoxicity, and apoptotic-inducing activity of ruthenium(II) polypyridyl complex. | 2010-07 |
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| DNA binding and gel electrophoresis studies of a copper (II) complex containing mixed aliphatic and aromatic dinitrogen ligands. | 2010-06 |
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| Tritopic phenanthroline and pyridine tail-tied aza-scorpiands. | 2010-05-21 |
|
| Stability of disubstituted copper complexes in the gas phase analyzed by electrospray ionization mass spectrometry. | 2010-05-15 |
|
| Bis[bis-(4,4'-dimethyl-2,2'-bipyridine)(10,11,12,13-tetra-hydro-dipyrido[3,2-a:2',3'-c]phenazine)ruthenium(II)] tetra-kis(perchlorate) acetonitrile disolvate monohydrate. | 2010-04-21 |
|
| Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity. | 2010-04-15 |
|
| Bis(2,9-dimethyl-1,10-phenanthroline-κN,N')(10,11,12,13-tetra-hydro-dipyrido[3,2-a:2',3'-c]phenazine-κN,N)ruthenium(II) bis-(perchlorate) dihydrate. | 2010-01-30 |
|
| 2,9-Bis(trichloro-meth-yl)-1,10-phenanthroline. | 2010-01-23 |
|
| Syntheses, structures and spectroscopy of uni- and bi-dentate nitrogen base complexes of silver(I) trifluoromethanesulfonate. | 2010-01-21 |
|
| Bis(2,2'-bipyridyl-κN,N')bis-(2-hydroxy-benzoato)-κO;κO,O-cadmium(II) methanol solvate. | 2010-01-16 |
|
| Synthesis, characterization, interaction with DNA and cytotoxicity in vitro of the complexes [M(dmphen)(CO3)].H2O [M=Pt(II), Pd(II)]. | 2010-01 |
|
| Dichlorido(2,9-dimethyl-1,10-phenanthroline)manganese(II) hemihydrate. | 2009-11-21 |
|
| (6,6'-Dimethyl-2,2'-bipyridine-κN,N')diiodidozinc(II). | 2009-10-28 |
|
| Dibromido(6,6'-dimethyl-2,2'-bipyridine-κN,N')zinc(II). | 2009-10-07 |
|
| Dichlorido(6,6'-dimethyl-2,2'-bipyridine-κN,N')zinc(II). | 2009-09-26 |
|
| Dichlorido(2,9-dimethyl-1,10-phenanthroline-κN,N')copper(II). | 2009-09-05 |
|
| Equilibrium and ab initio computational studies on the adduct formation of 1,3-diketonato-lithium(I), -sodium(I) and -potassium(I) with 1,10-phenanthroline and its 2,9-dimethyl derivatives. | 2009-06-15 |
|
| Dichloridobis(phenanthridine-κN)zinc(II). | 2009-06-06 |
|
| Capturing and analyzing the excited-state structure of a Cu(I) phenanthroline complex by time-resolved diffraction and theoretical calculations. | 2009-05-13 |
|
| Synthesis, crystal structure, cytotoxic activities and DNA-binding properties of new binuclear copper(II) complexes bridged by N,N'-bis(N-hydroxyethylaminoethyl)oxamide. | 2009-05 |
|
| Bis(phenanthridinium) hexa-chloridoplatinate(IV) dimethyl sulfoxide disolvate. | 2009-01-28 |
|
| Aqua-(2,9-dimethyl-1,10-phenanthroline-κN,N')bis-(2-hydroxy-benzoato-κO)manganese(II) 2,9-dimethyl-1,10-phenanthroline hemisolvate. | 2009-01-14 |
|
| Diaqua-(2,9-dimethyl-1,10-phenanthroline-κN,N')(4-hydroxy-benzoato-κO,O')cobalt(II) nitrate dihydrate. | 2008-11-22 |
|
| (2,9-Dimethyl-1,10-phenanthroline-κN,N')bis-(2-hydroxy-benzoato-κO)copper(II). | 2008-11-13 |
|
| (2,9-Dimethyl-1,10-phenanthroline-κN,N')(4-hydroxy-benzoato-κO,O')(nitrato-κO)copper(II). | 2008-10-31 |
|
| New chemistry of olefin complexes of platinum(II) unravelled by basic conditions: synthesis and properties of elusive cationic species. | 2008-10-21 |
|
| A new approach for the detection of ethylene using silica-supported palladium complexes. | 2008-10-06 |
|
| (4,7-Diphenyl-1,10-phenanthroline-κN,N')diiodidomercury(II). | 2008-09-27 |
|
| Theoretical characterization of a typical hole/exciton-blocking material bathocuproine and its analogues. | 2008-09-25 |
|
| Bis(2,4,6-trimethyl-pyridinium) hexa-chloridoplatinate(IV). | 2008-09-13 |
|
| Dichlorido(6-methyl-2,2'-bipyridine-κN,N')zinc(II). | 2008-09-13 |
|
| (4,4'-Dimethyl-2,2'-bipyridine-κN,N')diiodidomercury(II). | 2008-09-13 |
|
| An unusual two-dimensional hydrogen-bonding network in bis(2,9-dimethyl-1,10-phenanthrolin-1-ium) peroxodisulfate dihydrate. | 2008-09 |
|
| Bis(2,6-dimethyl-pyridinium) hexa-chlorido-platinate(IV). | 2008-08-09 |
|
| A second polymorph of aqua-(2,9-di-methyl-1,10-phenanthroline-κN,N')bis-(formato-κO)copper(II). | 2008-07-26 |
|
| Three-dimensional local structure of photoexcited Cu diimine complex refined by quantitative XANES analysis. | 2008-06-19 |
|
| (2,9-Dimethyl-1,10-phenanthroline-κN,N')bis-(2-hydroxy-benzoato)-κO;κO,O'-cobalt(II). | 2008-04-30 |
|
| Apoptosis of cultured astrocytes induced by the copper and neocuproine complex through oxidative stress and JNK activation. | 2008-03 |
|
| Bis(benzoato-κO,O')(2,9-dimethyl-1,10-phenanthroline-κN,N')cobalt(II). | 2008-01-09 |
|
| Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide. | 2008 |
|
| Synchronized fluxional motion and cyclometalation of ligands in platinum(II) complexes. | 2007-12-10 |
|
| Synthesis, crystal structure and magnetic properties of novel heterobimetallic malonate-bridged MIIReIV complexes (M = Mn, Fe, Co and Ni). | 2007-12-07 |
|
| RNA cleavage by 2,9-diamino-1,10-phenanthroline PNA conjugates. | 2007 |
|
| Utilization of activating and masking effects by ligands for highly selective catalytic spectrophotometric determination of copper and iron in natural waters. | 2003-08-29 |
|
| Investigation of the reaction of copper(I) with 2,9-dimethyl-1,10-phenanthroline at trace level by thermal lensing. | 2002-07-03 |
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DTXSID5060065
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SUBSTANCE RECORD