Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H20NO4P |
| Molecular Weight | 225.2225 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC(OCC)P(O)(=O)CCCN
InChI
InChIKey=QIIVUOWTHWIXFO-UHFFFAOYSA-N
InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo. | 2010-10 |
|
| Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348). | 2009-09 |
|
| Pharmacological and autoradiographic studies on the pathophysiological role of GABA(B) receptors in the dystonic hamster: pronounced antidystonic effects of baclofen after striatal injections. | 2009-08-18 |
|
| Comparative pharmacological activity of optical isomers of phenibut. | 2008-03-31 |
|
| Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone. | 2008-02 |
|
| GABAB receptor blockade enhances theta and gamma rhythms in the hippocampus of behaving rats. | 2007 |
|
| Detection of gamma-aminobutyric acid-induced glutamate release in acute mouse hippocampal slices with a patch sensor. | 2006-06-01 |
|
| Discriminative stimulus effects of gamma-hydroxybutyrate: role of training dose. | 2006-04 |
|
| Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors. | 2004-03 |
|
| Hindquarters vasoconstriction through central GABA(B) receptors in conscious rats. | 2003-07 |
|
| The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system. | 2003 |
|
| Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria). | 2002-07 |
|
| International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function. | 2002-06 |
|
| GABA-B-related activity in processing of transcallosal response in cat motor cortex. | 2002-05-15 |
|
| The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. | 2000-11 |
|
| Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. | 1997-03-20 |
|
| CGP 35348 and CGP 55845A block the baclofen-induced depression of dorsal root evoked potentials in lumbar motoneurons of the neonatal rat. | 1996-08-23 |
|
| Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models. | 1995-09 |
|
| Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. | 1995-08-18 |
|
| Antagonism of baclofen-induced depression of whole-cell synaptic currents in spinal dorsal horn neurones by the potent GABAB antagonist CGP55845. | 1993-12 |
|
| Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse. | 1993-04 |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
123690-79-9
Created by
admin on Mon Mar 31 18:57:22 GMT 2025 , Edited by admin on Mon Mar 31 18:57:22 GMT 2025
|
PRIMARY | |||
|
DTXSID70154064
Created by
admin on Mon Mar 31 18:57:22 GMT 2025 , Edited by admin on Mon Mar 31 18:57:22 GMT 2025
|
PRIMARY | |||
|
87TI61875H
Created by
admin on Mon Mar 31 18:57:22 GMT 2025 , Edited by admin on Mon Mar 31 18:57:22 GMT 2025
|
PRIMARY | |||
|
107699
Created by
admin on Mon Mar 31 18:57:22 GMT 2025 , Edited by admin on Mon Mar 31 18:57:22 GMT 2025
|
PRIMARY | |||
|
CGP-35348
Created by
admin on Mon Mar 31 18:57:22 GMT 2025 , Edited by admin on Mon Mar 31 18:57:22 GMT 2025
|
PRIMARY |
SUBSTANCE RECORD
