CGP-35348

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H20NO4P
Molecular Weight	225.2225
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CCOC(OCC)P(O)(=O)CCCN

InChI

InChIKey=QIIVUOWTHWIXFO-UHFFFAOYSA-N

InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
GABA-B receptor 1 3	Antagonist 2,778		27.0 nM [IC50]

PubMed

PubMed

Show entries

Title	Date	PubMed
Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse.	1993 Apr	8390321
Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.	1995 Sep	7562514
CGP 35348 and CGP 55845A block the baclofen-induced depression of dorsal root evoked potentials in lumbar motoneurons of the neonatal rat.	1996 Aug 23	8878094
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.	1997 Mar 20	9069281
The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system.	2003	12732255

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Name

Type

Language

CGP-35348

Common Name

English

3-AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID

Systematic Name

English

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Code System

Code

Type

Description

CAS

123690-79-9

PRIMARY

EPA CompTox

DTXSID70154064

PRIMARY

FDA UNII

87TI61875H

PRIMARY

PUBCHEM

107699

PRIMARY

WIKIPEDIA

CGP-35348

PRIMARY

Showing 1 to 5 of 5 entries

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SUBSTANCE RECORD


					87TI61875H

CGP-35348