| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H12O4 |
| Molecular Weight | 196.1999 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(=CC(OC)=C1O)C(C)=O
InChI
InChIKey=OJOBTAOGJIWAGB-UHFFFAOYSA-N
InChI=1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3
Acetosyringone is a naturally occurring compound found in a wide variety of plants. It is best known for its involvement in plant-pathogen recognition and its biotechnical applications for enhancing plant transformation efficiency. There has been limited investigation of human or animal applications. In one instance Acetosyringone demonstrated accelerated hair regrowth in a mouse model.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
Sample Use Guides
The hair on the back of 9-week old male C3H/He mice was clipped off and the clipped area was treated with softening cream for 5 or 10 min and washed. After 24 hours a test sample of Acetosyringone (0.001, 0.01, 0.1, 0.5, 1.0 mg) was applied topically once per day for 1 or 3 days. Hair regrowth was monitored relative to controls. Acetosyringone promoted significantly greater hair regrowth at all concentrations compared to controls and did not cause skin irritation.
Route of Administration:
Unknown
SUBSTANCE RECORD
