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Details

Stereochemistry ACHIRAL
Molecular Formula C10H12O4
Molecular Weight 196.1999
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETOSYRINGONE

SMILES

COC1=CC(=CC(OC)=C1O)C(C)=O

InChI

InChIKey=OJOBTAOGJIWAGB-UHFFFAOYSA-N
InChI=1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3

HIDE SMILES / InChI

Molecular Formula C10H12O4
Molecular Weight 196.1999
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Acetosyringone is a naturally occurring compound found in a wide variety of plants. It is best known for its involvement in plant-pathogen recognition and its biotechnical applications for enhancing plant transformation efficiency. There has been limited investigation of human or animal applications. In one instance Acetosyringone demonstrated accelerated hair regrowth in a mouse model.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
The hair on the back of 9-week old male C3H/He mice was clipped off and the clipped area was treated with softening cream for 5 or 10 min and washed. After 24 hours a test sample of Acetosyringone (0.001, 0.01, 0.1, 0.5, 1.0 mg) was applied topically once per day for 1 or 3 days. Hair regrowth was monitored relative to controls. Acetosyringone promoted significantly greater hair regrowth at all concentrations compared to controls and did not cause skin irritation.
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
866P45Y84S
Record Status Validated (UNII)
Record Version