BECLOTIAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16ClN4S.Cl
Molecular Weight	319.253
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].CC1=C(CCCl)SC=[N+]1CC2=C(N)N=C(C)N=C2

InChI

InChIKey=BPEQAFGUCPPRIB-UHFFFAOYSA-M

InChI=1S/C12H16ClN4S.ClH/c1-8-11(3-4-13)18-7-17(8)6-10-5-15-9(2)16-12(10)14;/h5,7H,3-4,6H2,1-2H3,(H2,14,15,16);1H/q+1;/p-1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/704151

Beclotiamine (or chloroethyl thiamine) had been studied for veterinary and showed anticoccidial activity against Eimeria tenella, although metabolites and related substances were inactive. Information about the nowadays application of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Rapid and sensitive determination of amprolium in chicken plasma by high-performance liquid chromatography with post-column reaction.	1997-06-06	9210457
Studies on the mode of action of beclotiamine on Eimeria tenella.	1978-10	704151
[Effect of beclotiamine on the thiamine requirements of Eimeria tenella and Eimeria acervulina].	1972-06	4672599

Patents

Name

Type

Language

BECLOTIAMINE

Official Name

English

BECLOTIAMINE [MI]

Preferred Name

English

beclotiamine [INN]

Common Name

English

3-((4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL)-5-(2-CHLOROETHYL)-4-METHYLTHIAZOLIUM CHLORIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45812