2-AMINO-6-CHLOROPURINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H4ClN5
Molecular Weight	169.572
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(NC=N2)C(Cl)=N1

InChI

InChIKey=RYYIULNRIVUMTQ-UHFFFAOYSA-N

InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
purine nucleotide biosynthetic process 1 Target ID: GO:0006164 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5638558	Inhibitor 8297

PubMed

Title	Date	PubMed
Synthesis of 2-alkyl-substituted-N6-methyladenine derivatives as potential adenosine receptor ligand.	2001 Dec	11794524
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.	2003 Dec	14714763
Three 2-aminopurine derivatives.	2003 Jan	12506238
Facilitation of addition-elimination reactions in pyrimidines and purines using trifluoroacetic acid in trifluoroethanol.	2003 Nov 21	14651112
Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages.	2005 Apr 15	15781401
Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity.	2005 Dec	16359173
Efficient N-arylation and N-alkenylation of the five DNA/RNA nucleobases.	2006 Nov 24	17109545
Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines.	2007	17454732
Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis.	2007 Sep	18428966
(Z)- and (E)-2-(1,2-dihydroxyethyl)methylenecyclopropane analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, absolute configuration, and antiviral activity.	2009 May 28	19397271

Patents

Name

Type

Language

2-AMINO-6-CHLOROPURINE

Systematic Name

English

1H-PURIN-2-AMINE, 6-CHLORO-

Systematic Name

English

9H-PURIN-2-AMINE, 6-CHLORO-

Systematic Name

English

6-CHLORO-2-AMINOPURINE

Systematic Name

English

PURINE, 2-AMINO-6-CHLORO-

Systematic Name

English

FAMCICLOVIR RELATED COMPOUND F

Common Name

English

6-CHLORO-7H-PURIN-2-AMINE

Systematic Name

English

FAMCICLOVIR RELATED COMPOUND F [USP-RS]

Common Name

English

6-CHLORO-2-PURINAMINE

Systematic Name

English

6-CHLORO-1H-PURIN-2-AMINE

Systematic Name

English

NSC-29570

Code

English

6-CHLOROGUANINE

Common Name

English

6-CHLORO-9H-PURIN-2-YL-2-AMINE

Common Name

English

2-AMINO-6-CHLORO-9H-PURINE

Systematic Name

English

Code System Code Type Description

CHEBI

72345