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Details

Stereochemistry ACHIRAL
Molecular Formula C12H13N3O2
Molecular Weight 231.2505
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FARAMPATOR

SMILES

O=C(N1CCCCC1)C2=CC3=NON=C3C=C2

InChI

InChIKey=XFVRBYKKGGDPAJ-UHFFFAOYSA-N
InChI=1S/C12H13N3O2/c16-12(15-6-2-1-3-7-15)9-4-5-10-11(8-9)14-17-13-10/h4-5,8H,1-3,6-7H2

HIDE SMILES / InChI

Description

Farampator (CX 691, ORG 24448 or (1-(benzofurazan-5-ylcarbonyl) piperidine)) is a positive allosteric modulator of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors. Farampator exerts antipsychotic and cognitive enhancing properties.

CNS Activity

CNS Active
4,002

Originator

Cortex Pharmaceuticals
1

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
Glutamate receptor ionotropic, AMPA 3
4
Positive Allosteric Modulator
186
 14.0 µM [EC50]

PubMed

Patents

06110935
1
06313115
1
06730677
1

Sample Use Guides

In Vivo Use Guide
Farampator (500 mg) unequivocally improved short-term memory but appeared to impair episodic memory.
Route of Administration: Oral
ACTIVE MOIETY
Structure of FARAMPATOR
NIH
NCATS
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