PNU-142721 MESYLATE

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H11ClN4OS.CH4O3S
Molecular Weight	402.876
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PNU-142721 MESYLATE

SMILES

CS(O)(=O)=O.C[C@H](SC1=NC(N)=CC(Cl)=N1)C2=NC=C3OC=CC3=C2

InChI

InChIKey=DACCRIAOWPHTII-FJXQXJEOSA-N

InChI=1S/C13H11ClN4OS.CH4O3S/c1-7(20-13-17-11(14)5-12(15)18-13)9-4-8-2-3-19-10(8)6-16-9;1-5(2,3)4/h2-7H,1H3,(H2,15,17,18);1H3,(H,2,3,4)/t7-;/m0./s1

HIDE SMILES / InChI

Approval Year

PubMed

Show entries

Title	Date	PubMed
(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.	1998 Apr 23	9554867
Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant.	2002 Mar	11895437

Showing 1 to 2 of 2 entries

Patents

Show entries

Name

Type

Language

PNU-142721 MESYLATE

Code

English

4-PYRIMIDINAMINE, 6-CHLORO-2-(((1S)-1-FURO(2,3-C)PYRIDIN-5-YLETHYL)THIO)-, METHANESULFONATE (1:1)

Systematic Name

English

4-AMINO-6-CHLORO-2-(1-FURO(2,3C)PYRIDIN-5-YL)ETHYLTHIO-PYRIMIDENE MESYLATE, (-)-(S)

Common Name

English

PNU-142721E

Code

English

Showing 1 to 4 of 4 entries

Show entries

Code System

Code

Type

Description

FDA UNII

7QH6XJ3PLD

PRIMARY

PUBCHEM

131842441

PRIMARY

CAS

185220-05-7

PRIMARY

Showing 1 to 3 of 3 entries

PARENT (SALT/SOLVATE)


					U3D0LYB7P0

SUBSTANCE RECORD


					7QH6XJ3PLD

PNU-142721 MESYLATE