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Details

Stereochemistry ACHIRAL
Molecular Formula Ni
Molecular Weight 58.6934
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NICKEL

SMILES

[Ni]

InChI

InChIKey=PXHVJJICTQNCMI-UHFFFAOYSA-N
InChI=1S/Ni

HIDE SMILES / InChI

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Nickel-induced proliferation of both memory and naive T cells in patch test-negative individuals.
1999 Aug
Ni2+ transport by the human Na+/Ca2+ exchanger expressed in Sf9 cells.
1999 May
Inactivation properties of human recombinant class E calcium channels.
2000 Feb
Lead targets GRP78, a molecular chaperone, in C6 rat glioma cells.
2000 Mar 15
Involvement of the glycoproteic Ib-V-IX complex in nickel-induced platelet activation.
2001 Mar
Nickel requires hypoxia-inducible factor-1 alpha, not redox signaling, to induce plasminogen activator inhibitor-1.
2001 Sep
Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.
2002 Apr
Nickel-specific CD4(+) and CD8(+) T cells display distinct migratory responses to chemokines produced during allergic contact dermatitis.
2002 Jun
A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel.
2003 May 19
Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A.
2003 Nov 1
Metal-protein complex-mediated transport and delivery of Ni2+ to TCR/MHC contact sites in nickel-specific human T cell activation.
2004 Feb 1
What is responsible for the carcinogenicity of PM2.5?
2004 Oct
Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells.
2005 Aug 15
Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals.
2006 Dec
Activation of MAP kinases by hexavalent chromium, manganese and nickel in human lung epithelial cells.
2006 Dec 1
A hint for the function of human Sco1 from different structures.
2006 Jun 6
Insulin-like growth factors (IGF) I and II utilize different calcium signaling pathways in a primary human parathyroid cell culture model.
2006 Mar
Allergic contact dermatitis to nickel: modified in vitro test protocols for better detection of allergen-specific response.
2007 Feb
Gene expression time course in the human skin during elicitation of allergic contact dermatitis.
2007 Nov
Characterization and distribution of the selected metals in the scalp hair of cancer patients in comparison with normal donors.
2007 Sep
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.
2009 Jul
Effect of short-time exposures to nickel and lead on brain monoamine oxidase from Danio rerio and Poecilia reticulata.
2009 Jun
Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells.
2009 Mar 16
Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells.
2010 Jan 5
Nickel sensitisation in mice: a critical appraisal.
2010 Jun
Patents

Patents

03937759
2
03954868
2
03956314
2
03963706
5
03969463
10
03978097
6
03989701
1
03992392
2
04018790
1
04021539
10
04024187
1
04024272
3
04026894
1
04029648
2
04031219
2
04031226
4
04032536
1
04041058
2
04048198
1
04072696
2
04087530
1
04110333
4
04126615
1
04126688
4
04137325
1
04138567
1
04151199
1
04169150
1
04181802
1
04200588
2
04201584
1
04209514
1
04210647
1
04216221
1
04227000
6
04243813
1
04268693
1
04280957
6
04307237
7
04313755
1
04313949
1
04321354
1
04324719
1
04335127
5
04354973
1
04355177
3
04360525
1
04376074
4
04377587
1
04382150
1
04400386
2
Name Type Language
NICKEL
FCC   HSDB   MI   VANDF   WHO-DD  
Systematic Name English
RANEY NICKEL [MI]
Common Name English
NICKEL [VANDF]
Common Name English
NICCOLUM METALLICUM
HPUS  
Common Name English
NICKEL [MI]
Common Name English
Nickel [WHO-DD]
Common Name English
NICCOLUM METALLICUM [HPUS]
Common Name English
NICKEL [FCC]
Common Name English
NI
Common Name English
NICKEL [HSDB]
Common Name English
METALLIC NICKEL
Common Name English
CARBONYL-NICKEL
Systematic Name English
NICKEL, METALLIC AND ALLOYS [IARC]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 184.1537
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
NDF-RT N0000185508
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
NCI_THESAURUS C896
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
DSLD 93 (Number of products:378)
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
NCI_THESAURUS C637
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
NCI_THESAURUS C45383
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
Code System Code Type Description
CHEBI
28112
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-111-4
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
CAS
7440-02-0
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
NCI_THESAURUS
C690
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
PUBCHEM
935
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
EPA CompTox
DTXSID2020925
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
SMS_ID
100000127669
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
MESH
D009532
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
RXCUI
1311629
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m7853
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY Merck Index
HSDB
1096
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
MERCK INDEX
m9495
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY Merck Index
NDF-RT
N0000171131
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY Allergens [Chemical/Ingredient]
EVMPD
SUB33726
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
WIKIPEDIA
Raney nickel
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
NDF-RT
N0000184306
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY Cell-mediated Immunity [PE]
NDF-RT
N0000175629
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY Increased Histamine Release [PE]
FDA UNII
7OV03QG267
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
DAILYMED
7OV03QG267
Created by admin on Fri Dec 15 16:38:48 GMT 2023 , Edited by admin on Fri Dec 15 16:38:48 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of NICKEL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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