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Details

Stereochemistry ACHIRAL
Molecular Formula C11H16N2O3
Molecular Weight 224.2563
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of VINBARBITAL

SMILES

CC\C=C(/C)C1(CC)C(=O)NC(=O)NC1=O

InChI

InChIKey=RAFOHKSPUDGZPR-VOTSOKGWSA-N
InChI=1S/C11H16N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h6H,4-5H2,1-3H3,(H2,12,13,14,15,16)/b7-6+

HIDE SMILES / InChI
VINBARBITAL, a barbiturate derivative, is a hypnotic drug. Also, it was used for analgesia and anesthesia in obstetrics.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
DELVINAL

Approved Use

The best therapeutic results are obtained in patients with psychoneuroses, manic-depressive manic or mixed psychoses, toxic or infectious psychoses—and, to a lesser extent, in patients with involutional melancholia.
Doses

Doses

DosePopulationAdverse events​
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Other AEs: Epigastric discomfort, Nausea...
Other AEs:
Epigastric discomfort (2 patients)
Nausea (2 patients)
Dizziness (1 patient)
Sweating (3 patients)
Apprehension (1 patient)
Fatigue (3 patients)
Sources:
AEs

AEs

AESignificanceDosePopulation
Apprehension 1 patient
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Dizziness 1 patient
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Epigastric discomfort 2 patients
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Nausea 2 patients
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Fatigue 3 patients
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Sweating 3 patients
32 mg single, oral
Recommended
Dose: 32 mg
Route: oral
Route: single
Dose: 32 mg
Sources:
healthy
n = 10
Health Status: healthy
Population Size: 10
Sources:
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer

Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
yes
PubMed

PubMed

TitleDatePubMed
Name Type Language
VINBARBITAL
INN   WHO-DD  
INN  
Official Name English
VINBARBITONE
Common Name English
vinbarbital [INN]
Common Name English
NSC-117442
Code English
BUTENEMAL
Common Name English
5-ETHYL-5-(1-METHYL-1-BUTENYL)BARBITURIC ACID
Systematic Name English
Vinbarbital [WHO-DD]
Common Name English
VINBARBITAL SODIUM FREE ACID [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C67084
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
WHO-VATC QN05CA09
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
DEA NO. 2100
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
WHO-ATC N05CA09
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
Code System Code Type Description
INN
766
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
CAS
75016-38-5
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
ALTERNATIVE
DRUG CENTRAL
3849
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
PUBCHEM
5284636
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
ECHA (EC/EINECS)
204-739-1
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
RXCUI
89811
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY RxNorm
FDA UNII
7NZH2C1T6O
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
MERCK INDEX
m985
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
NCI_THESAURUS
C76530
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
WIKIPEDIA
VINBARBITAL
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
EVMPD
SUB00051MIG
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
EPA CompTox
DTXSID1023738
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
DRUG BANK
DB13377
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
SMS_ID
100000079105
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
ChEMBL
CHEMBL503565
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
CAS
125-42-8
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY
NSC
117442
Created by admin on Sat Dec 16 17:42:42 UTC 2023 , Edited by admin on Sat Dec 16 17:42:42 UTC 2023
PRIMARY