U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C10H14O2
Molecular Weight 166.217
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IDRAMANTONE

SMILES

OC12CC3CC(C1)C(=O)C(C3)C2

InChI

InChIKey=TZBDEVBNMSLVKT-UHFFFAOYSA-N
InChI=1S/C10H14O2/c11-9-7-1-6-2-8(9)5-10(12,3-6)4-7/h6-8,12H,1-5H2

HIDE SMILES / InChI

Description

Idramantone (Kemantane) is a biologically active compound first synthesized and pharmacologically studied at the V. V. Zakusov Science Research Institute of Pharmacology, Russian Academy of Medical Sciences. Idramantone has immunostimulatory properties, which are particularly effective in the treatment of autoimmune diseases of the vascular system of the limbs, chronic bronchitis, bronchial asthma, aphthous stomatitis, herpes, and others. Idramantone also has an antiparkinsonism action. The compound has antiamnestic properties, which experimental data indicate are comparable in strength to those of memantine. Idramantone has cerebrovascular properties, increasing the blood supply in the ischemic brain. In addition, Idramantone and its derivatives are used in the electronics industry.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown
Primary
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
0.2g 3 times daily
Route of Administration: Oral
In Vitro Use Guide
Unknown