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Details

Stereochemistry ACHIRAL
Molecular Formula C8H15NO3
Molecular Weight 173.2096
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACEXAMIC ACID

SMILES

CC(=O)NCCCCCC(O)=O

InChI

InChIKey=WDSCBUNMANHPFH-UHFFFAOYSA-N
InChI=1S/C8H15NO3/c1-7(10)9-6-4-2-3-5-8(11)12/h2-6H2,1H3,(H,9,10)(H,11,12)

HIDE SMILES / InChI

Description

Acexamic acid (N-acetyl-amino-6-hexanoic acid) is a drug used as a cicatrization helper. Some studies show that the acexamic acid prevents the formation the connective inflamed tissue and enables its healing. The association from acexamic acid with zinc, zinc acexamate, has been used in the treatment of gastric and duodenal ulcer and in the prevention of gastric ulcer induced by nonsteroidal anti-inflammatory drugs.

Originator

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Acemin ointment
Primary
Acemin ointment
PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Outer: 5% ointment is applied to the disinfected wound surface daily. The course of treatment is from 10 to 30 days.
Route of Administration: Topical
In Vitro Use Guide
The mouse fibroblast cell line (NCTC Clone L 929) was maintained as stock culture in a minimum essential medium (MEM) supplemented with 10% calf serum and 200 i.u./ml G penicillin and 100 pg/d streptomycin. Cultures for growth studies were established by inoculating 7 X l0^4 cells in 2 ml medium in 35-mm plastic tissue culture dishes. They were maintained for 24 h to obtain a good attachment, then incubated in 5% calf serum medium supplemented or not with the drugs tested. Acexamic acid increased the growth rate of L 929 when used at a concentration of 0.001%
Name Type Language
ACEXAMIC ACID
INN   MART.   WHO-DD  
INN  
Official Name English
ACEMIN
Common Name English
ACETAMIDOCAPROIC ACID
INCI  
INCI  
Official Name English
6-(ACETYLAMINO)HEXANOIC ACID
Systematic Name English
N-ACETYL-6-AMINOHEXANOIC ACID
Systematic Name English
HEXANOIC ACID, 6-ACETAMIDO-
Common Name English
CY-153
Code English
6-ACETAMIDOCAPROIC ACID
Systematic Name English
ACEXAMIC ACID [MART.]
Common Name English
ACETAMIDOCAPROIC ACID [INCI]
Common Name English
HEXANOIC ACID, 6-(ACETYLAMINO)-
Common Name English
ACETAMINOCAPROIC ACID
Systematic Name English
NSC-12945
Code English
ACEXAMIC ACID [INN]
Common Name English
.EPSILON.-ACETAMIDOCAPROIC ACID
MI  
Systematic Name English
N-ACETYL-.EPSILON.-AMINOCAPROIC ACID
Systematic Name English
6-ACETAMIDOHEXANOIC ACID
Systematic Name English
ACEXAMIC ACID [WHO-DD]
Common Name English
CY 153
Code English
.EPSILON.-ACETAMIDOCAPROIC ACID [MI]
Common Name English
Code System Code Type Description
EPA CompTox
57-08-9
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
PUBCHEM
2005
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
ChEMBL
CHEMBL2105922
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
EVMPD
SUB05234MIG
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
RXCUI
15978
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY RxNorm
MESH
C018802
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
CAS
57-08-9
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
MERCK INDEX
M1316
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY Merck Index
ECHA (EC/EINECS)
200-310-8
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
NCI_THESAURUS
C80535
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY
INN
2246
Created by admin on Tue Mar 06 12:07:02 UTC 2018 , Edited by admin on Tue Mar 06 12:07:02 UTC 2018
PRIMARY