Details
Stereochemistry | ACHIRAL |
Molecular Formula | C27H29NO |
Molecular Weight | 383.5253 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCN1C=C(C(=O)C2=C3C=CC=CC3=C(CCC)C=C2)C4=C1C=CC=C4
InChI
InChIKey=AKGUMDFQXWZHHS-UHFFFAOYSA-N
InChI=1S/C27H29NO/c1-3-5-10-18-28-19-25(23-14-8-9-15-26(23)28)27(29)24-17-16-20(11-4-2)21-12-6-7-13-22(21)24/h6-9,12-17,19H,3-5,10-11,18H2,1-2H3
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: P21554|||Q5UB37 Gene ID: 1268.0 Gene Symbol: CNR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/15582455 |
0.65 nM [Ki] | ||
Target ID: P34972 Gene ID: 1269.0 Gene Symbol: CNR2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/15582455 |
1.1 nM [Ki] |
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WIKIPEDIA |
Designer-drugs-JWH-182
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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Code System | Code | Type | Description | ||
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7H0XW15CON
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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JWH-182
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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PRIMARY | JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM.1 Its effects in cells and animals are unknown. | ||
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824960-02-3
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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45268702
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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JWH-182
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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PRIMARY | JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with Ki values of 0.46nM at CB1 and 0.69nM at CB2. It is one of the most potent 4-substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity (i.e. lower Ki) at CB1 than both its 4-methyl and 4-n-propyl homologues JWH-122 (CB1 Ki 0.69nM) and JWH-182 (CB1 Ki 0.65nM) respectively, and than the 4-methoxy compound JWH-081 (CB1 Ki 1.2nM). | ||
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DTXSID401337155
Created by
admin on Fri Dec 15 16:31:14 GMT 2023 , Edited by admin on Fri Dec 15 16:31:14 GMT 2023
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ACTIVE MOIETY