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Details

Stereochemistry RACEMIC
Molecular Formula C22H29N3O4
Molecular Weight 399.4834
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of PERADOXIME

SMILES

COC1=CC(C=NOCC(O)CN2CCN(CC2)C3=CC=CC=C3OC)=CC=C1

InChI

InChIKey=QSOFMSXQETVQGE-HAHDFKILSA-N
InChI=1S/C22H29N3O4/c1-27-20-7-5-6-18(14-20)15-23-29-17-19(26)16-24-10-12-25(13-11-24)21-8-3-4-9-22(21)28-2/h3-9,14-15,19,26H,10-13,16-17H2,1-2H3/b23-15-

HIDE SMILES / InChI
Peradoxime is an antihypertensive agent. In normal animals, 37-48% of the radioactivity from an oral dose of labeled peradoxime or parenteral dose was excreted in the urine, and 48-50% in the feces. Biliary and urinary metabolites of peradoxime were principally found as conjugates with glucuronic acid.

Approval Year

PubMed

PubMed

TitleDatePubMed
Enterohepatic circulation in rat and dog of 14C-0-[3-(4-less than 2-methoxyphenyl greater than-1-piperazinyl)-2-hydroxypropyl]-3-methoxy-benzaldoxim dihydrochloride and it's demethylated metabolite.
1981

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Rat data
Single dose - 2 mg/kg of body weight
Route of Administration: Oral
Name Type Language
PERADOXIME
INN  
INN  
Official Name English
peradoxime [INN]
Common Name English
M-ANISALDEHYDE O-(2-HYDROXY-3-(4-(O-METHOXYPHENYL)-1-PIPERAZINYL)PROPYL) OXIME
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C241
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
Code System Code Type Description
SMS_ID
100000082521
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
FDA UNII
7A977PW795
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
PUBCHEM
163138
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
INN
4606
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
NCI_THESAURUS
C81385
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
EVMPD
SUB09711MIG
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105455
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY
CAS
67254-81-3
Created by admin on Fri Dec 15 15:40:01 GMT 2023 , Edited by admin on Fri Dec 15 15:40:01 GMT 2023
PRIMARY