BENZYL FORMATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H8O2
Molecular Weight	136.1479
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=COCC1=CC=CC=C1

InChI

InChIKey=UYWQUFXKFGHYNT-UHFFFAOYSA-N

InChI=1S/C8H8O2/c9-7-10-6-8-4-2-1-3-5-8/h1-5,7H,6H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Ionisations within a subtilisin-glyoxal inhibitor complex.	2005-05-20	15848134
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.	2005-04-12	15824335
Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2.	2005-03	15730543
Antiepileptic drugs alter reproductive endocrine hormones in men with epilepsy.	2005-02	15679699
Asymmetric total syntheses of tuberostemonine, didehydrotuberostemonine, and 13-epituberostemonine.	2005-01-12	15631472
Purification and characterization of a high molecular mass serine carboxypeptidase from Monascus pilosus.	2004-12	15592905
Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: a randomized, double-blind, placebo-controlled trial.	2004-12	15571523
In vitro-in vivo evaluation of supercritical processed solid dispersions: permeability and viability assessment in Caco-2 cells.	2004-12	15468328
N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.	2004-12	15292462
A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei.	2004-11-12	15326171
Chemoenzymatic preparation of optically active trans-cyclohexane-1,2-diamine derivatives: an efficient synthesis of the analgesic U-(-)-50,488.	2004-11-05	15472932
Factors controlling the complex architecture of native and modified cyclodextrins with dipeptide (Z-Glu-Tyr) studied by microcalorimetry and NMR spectroscopy: critical effects of peripheral bis-trimethylamination and cavity size.	2004-11-03	15506789
Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients.	2004-11	15519127
Carbamazepine enhances discriminative memory in a rat model of epilepsy.	2004-11	15509245
Fracture risk associated with use of antiepileptic drugs.	2004-11	15509233
Novel urea-linked cinchona-calixarene hybrid-type receptors for efficient chromatographic enantiomer separation of carbamate-protected cyclic amino acids.	2004-10-22	15543978
Subtype selective substrates for histone deacetylases.	2004-10-07	15456267
Worsening of seizures by oxcarbazepine in juvenile idiopathic generalized epilepsies.	2004-10	15461683
What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs?	2004-10	15380112
Microorganisms degrading chlorobenzene via a meta-cleavage pathway harbor highly similar chlorocatechol 2,3-dioxygenase-encoding gene clusters.	2004-10	15340793
Study of in-vitro release characteristics of carbamazepine extended release semisolid matrix filled capsules based on Gelucires.	2004-09	15521328
Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism.	2004-08-27	15205454
[Influence of coadministered antiepileptic drugs on serum antiepileptic drug concentrations in epileptic patients -quantitative analysis based on suitable transforming factor].	2004-07	15235228
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.	2004-06	15153086
The effectiveness of divalproate in all forms of mania and the broader bipolar spectrum: many questions, few answers.	2004-04	15121342
A surface-modified dendrimer set for potential application as drug delivery vehicles: synthesis, in vitro toxicity, and intracellular localization.	2004-03-05	15007808
The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model.	2004-03	14975678
Oxcarbazepine antinociception in animals with inflammatory pain or painful diabetic neuropathy.	2004-02-06	14756685
Neuronal MDR-1 gene expression and persistent low levels of anticonvulsants in a child with refractory epilepsy.	2004-02	14749549
Surfactant-facilitated crystallization of dihydrate carbamazepine during dissolution of anhydrous polymorph.	2004-02	14705201
Coordination modes vs. antitumor activity: synthesis and antitumor activity of novel platinum(II) complexes of N-substituted amino dicarboxylic acids.	2004-01	14659638
Pitch perception abnormality as a side effect of carbamazepine.	2004-01	14642372
Chronic carbamazepine treatment increases myristoylated alanine-rich C kinase substrate phosphorylation in the rat cerebral cortex via down-regulation of calcineurin A alpha.	2003-12-19	14642444
Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats.	2003-12	14636316
Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems.	2003-11	14592695
Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants.	2003-09-15	13678654
Evaluation of an immortalized retinal endothelial cell line as an in vitro model for drug transport studies across the blood-retinal barrier.	2003-09	14567628
Method for multiresidue determination of halogenated aromatics and PAHs in combustion-related samples.	2003-08-15	12953881
Simultaneous plasma lamotrigine analysis with carbamazepine, carbamazepine 10,11 epoxide, primidone, phenytoin, phenobarbital, and PEMA by micellar electrokinetic capillary chromatography (MECC).	2003-08-12	12908944
N-hydroxyethyl-piperidine and -pyrrolidine homoazasugars: preparation and evaluation of glycosidase inhibitory activity.	2003-07-31	12837540
Synthesis and reactions of fluorous carbobenzyloxy (FCbz) derivatives of alpha-amino acids.	2003-06-13	12790566
How suitable are currently used carbamazepine immunoassays for quantifying carbamazepine-10,11-epoxide in serum samples?	2003-06	12766569
Bioaccumulation of PCBs and chlorinated pesticides in seals, fishes and invertebrates from the White Sea, Russia.	2003-05-01	12699922
Efficient protocols for the synthesis of enantiopure gamma-amino acids with proteinogenic side chains.	2003-05	12803497
Potassium trimethylsilanolate induced cleavage of 1,3-oxazolidin-2- and 5-ones, and application to the synthesis of (R)-salmeterol.	2003-04-07	12926383
Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects.	2003-04	12681003
Chemical modification of lipases with various hydrophobic groups improves their enantioselectivity in hydrolytic reactions.	2003-01	12882312
Simulation of the effect of patient nonadherence on plasma concentrations of carbamazepine from twice-daily extended-release capsules.	2003	14594524
An in vitro study of new antiepileptic drugs and astrocytes.	2003	14511393
Pharmacokinetic study of carbamazepine and its carbamazepine 10,11-epoxide metabolite in a group of female epileptic patients under chronic treatment.	2002-07-23	15010199

Patents

Name

Type

Language

BENZYL FORMATE

Systematic Name

English

FEMA NO. 2145

Preferred Name

English

BENZYL FORMATE [FHFI]

Common Name

English

FORMIC ACID, PHENYLMETHYL ESTER

Common Name

English

BENZYL ALCOHOL, FORMATE

Systematic Name

English

BENZYL METHANOATE

Systematic Name

English

NSC-8049

Code

English

FORMIC ACID, BENZYL ESTER

Common Name

English

PHENYLMETHYL FORMATE

Systematic Name

English

BENZYL FORMATE [FCC]

Common Name

English

BENZYL FORMATE [MI]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 172.515