Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H8O2 |
| Molecular Weight | 136.1479 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=COCC1=CC=CC=C1
InChI
InChIKey=UYWQUFXKFGHYNT-UHFFFAOYSA-N
InChI=1S/C8H8O2/c9-7-10-6-8-4-2-1-3-5-8/h1-5,7H,6H2
| Molecular Formula | C8H8O2 |
| Molecular Weight | 136.1479 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Ionisations within a subtilisin-glyoxal inhibitor complex. | 2005-05-20 |
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| Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. | 2005-04-12 |
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| Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2. | 2005-03 |
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| Antiepileptic drugs alter reproductive endocrine hormones in men with epilepsy. | 2005-02 |
|
| Asymmetric total syntheses of tuberostemonine, didehydrotuberostemonine, and 13-epituberostemonine. | 2005-01-12 |
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| Purification and characterization of a high molecular mass serine carboxypeptidase from Monascus pilosus. | 2004-12 |
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| Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: a randomized, double-blind, placebo-controlled trial. | 2004-12 |
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| In vitro-in vivo evaluation of supercritical processed solid dispersions: permeability and viability assessment in Caco-2 cells. | 2004-12 |
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| N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7. | 2004-12 |
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| A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei. | 2004-11-12 |
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| Chemoenzymatic preparation of optically active trans-cyclohexane-1,2-diamine derivatives: an efficient synthesis of the analgesic U-(-)-50,488. | 2004-11-05 |
|
| Factors controlling the complex architecture of native and modified cyclodextrins with dipeptide (Z-Glu-Tyr) studied by microcalorimetry and NMR spectroscopy: critical effects of peripheral bis-trimethylamination and cavity size. | 2004-11-03 |
|
| Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients. | 2004-11 |
|
| Carbamazepine enhances discriminative memory in a rat model of epilepsy. | 2004-11 |
|
| Fracture risk associated with use of antiepileptic drugs. | 2004-11 |
|
| Novel urea-linked cinchona-calixarene hybrid-type receptors for efficient chromatographic enantiomer separation of carbamate-protected cyclic amino acids. | 2004-10-22 |
|
| Subtype selective substrates for histone deacetylases. | 2004-10-07 |
|
| Worsening of seizures by oxcarbazepine in juvenile idiopathic generalized epilepsies. | 2004-10 |
|
| What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs? | 2004-10 |
|
| Microorganisms degrading chlorobenzene via a meta-cleavage pathway harbor highly similar chlorocatechol 2,3-dioxygenase-encoding gene clusters. | 2004-10 |
|
| Study of in-vitro release characteristics of carbamazepine extended release semisolid matrix filled capsules based on Gelucires. | 2004-09 |
|
| Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism. | 2004-08-27 |
|
| [Influence of coadministered antiepileptic drugs on serum antiepileptic drug concentrations in epileptic patients -quantitative analysis based on suitable transforming factor]. | 2004-07 |
|
| Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data. | 2004-06 |
|
| The effectiveness of divalproate in all forms of mania and the broader bipolar spectrum: many questions, few answers. | 2004-04 |
|
| A surface-modified dendrimer set for potential application as drug delivery vehicles: synthesis, in vitro toxicity, and intracellular localization. | 2004-03-05 |
|
| The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model. | 2004-03 |
|
| Oxcarbazepine antinociception in animals with inflammatory pain or painful diabetic neuropathy. | 2004-02-06 |
|
| Neuronal MDR-1 gene expression and persistent low levels of anticonvulsants in a child with refractory epilepsy. | 2004-02 |
|
| Surfactant-facilitated crystallization of dihydrate carbamazepine during dissolution of anhydrous polymorph. | 2004-02 |
|
| Coordination modes vs. antitumor activity: synthesis and antitumor activity of novel platinum(II) complexes of N-substituted amino dicarboxylic acids. | 2004-01 |
|
| Pitch perception abnormality as a side effect of carbamazepine. | 2004-01 |
|
| Chronic carbamazepine treatment increases myristoylated alanine-rich C kinase substrate phosphorylation in the rat cerebral cortex via down-regulation of calcineurin A alpha. | 2003-12-19 |
|
| Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats. | 2003-12 |
|
| Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems. | 2003-11 |
|
| Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants. | 2003-09-15 |
|
| Evaluation of an immortalized retinal endothelial cell line as an in vitro model for drug transport studies across the blood-retinal barrier. | 2003-09 |
|
| Method for multiresidue determination of halogenated aromatics and PAHs in combustion-related samples. | 2003-08-15 |
|
| Simultaneous plasma lamotrigine analysis with carbamazepine, carbamazepine 10,11 epoxide, primidone, phenytoin, phenobarbital, and PEMA by micellar electrokinetic capillary chromatography (MECC). | 2003-08-12 |
|
| N-hydroxyethyl-piperidine and -pyrrolidine homoazasugars: preparation and evaluation of glycosidase inhibitory activity. | 2003-07-31 |
|
| Synthesis and reactions of fluorous carbobenzyloxy (FCbz) derivatives of alpha-amino acids. | 2003-06-13 |
|
| How suitable are currently used carbamazepine immunoassays for quantifying carbamazepine-10,11-epoxide in serum samples? | 2003-06 |
|
| Bioaccumulation of PCBs and chlorinated pesticides in seals, fishes and invertebrates from the White Sea, Russia. | 2003-05-01 |
|
| Efficient protocols for the synthesis of enantiopure gamma-amino acids with proteinogenic side chains. | 2003-05 |
|
| Potassium trimethylsilanolate induced cleavage of 1,3-oxazolidin-2- and 5-ones, and application to the synthesis of (R)-salmeterol. | 2003-04-07 |
|
| Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects. | 2003-04 |
|
| Chemical modification of lipases with various hydrophobic groups improves their enantioselectivity in hydrolytic reactions. | 2003-01 |
|
| Simulation of the effect of patient nonadherence on plasma concentrations of carbamazepine from twice-daily extended-release capsules. | 2003 |
|
| An in vitro study of new antiepileptic drugs and astrocytes. | 2003 |
|
| Pharmacokinetic study of carbamazepine and its carbamazepine 10,11-epoxide metabolite in a group of female epileptic patients under chronic treatment. | 2002-07-23 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:40:40 GMT 2025
by
admin
on
Mon Mar 31 18:40:40 GMT 2025
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| Record UNII |
79GJF97O0Y
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| Record Status |
Validated (UNII)
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| Record Version |
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CFR |
21 CFR 172.515
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JECFA EVALUATION |
BENZYL FORMATE
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79GJF97O0Y
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m2407
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