ERBULOZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H27N3O5S
Molecular Weight	469.553
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)NC1=CC=C(SC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C4=CC=C(OC)C=C4)C=C1

InChI

InChIKey=KLEPCGBEXOCIGS-XUZZJYLKSA-N

InChI=1S/C24H27N3O5S/c1-3-30-23(28)26-19-6-10-22(11-7-19)33-15-21-14-31-24(32-21,16-27-13-12-25-17-27)18-4-8-20(29-2)9-5-18/h4-13,17,21H,3,14-16H2,1-2H3,(H,26,28)/t21-,24+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://adisinsight.springer.com/drugs/800003227 | https://www.ncbi.nlm.nih.gov/pubmed/8135472

Erbulozole (R 55104) is a water soluble congener of the microtubule inhibitor tubulozole, which has proven to possess anti-invasive, antitumoral and radiosensitizing capacities. Erbulozole development for the treatment of cancer has been discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed

Name

Type

Language

ERBULOZOLE

Official Name

English

erbulozole [INN]

Common Name

English

ERBULOZOLE [USAN]

Common Name

English

R 55104

Code

English

R-55104

Code

English

Erbulozole [WHO-DD]

Common Name

English

CARBAMIC ACID, (4-(((2-(1H-IMIDAZOL-1-YLMETHYL)-2-(4-METHOXYPHENYL)-1,3-DIOXOLAN-4-YL)METHYL)THIO)PHENYL)-, ETHYL ESTER, CIS-(±)-

Common Name

English

ETHYL (±)-CIS-P-(((2-(IMIDAZOL-1-YLMETHYL)-2-(P-METHOXYPHENYL)-1,3-DIOXOLAN-4-YL)METHYL)THIO)CARBANILATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C25974