Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C6H10O3 |
| Molecular Weight | 130.1418 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(C)C(=O)C(O)=O
InChI
InChIKey=JVQYSWDUAOAHFM-UHFFFAOYSA-N
InChI=1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Propionyl-CoA carboxylase deficiency with overflow of metabolites of isoleucine catabolism at all levels. | 1979 Jan 18 |
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| Determination of (S)- and (R)-2-oxo-3-methylvaleric acid in plasma of patients with maple syrup urine disease. | 1992 Jun 15 |
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| Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. | 2001 Mar 9 |
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| Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. | 2002 Jun |
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| Lacticin 3147 favours isoleucine transamination by Lactococcus lactis IFPL359 in a cheese-model system. | 2003 Apr |
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| Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids. | 2003 Jan 14 |
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| Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. | 2003 Jan 20 |
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| Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease. | 2003 Nov 20 |
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| Biosynthesis of branched-chain fatty acid in bacilli: FabD (malonyl-CoA:ACP transacylase) is not essential for in vitro biosynthesis of branched-chain fatty acids. | 2003 Oct |
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| Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. | 2003 Oct 15 |
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| Substrate specificity and kinetic isotope effect analysis of the Eschericia coli ketopantoate reductase. | 2003 Sep 30 |
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| Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. | 2004 |
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| A conditional marker gene allowing both positive and negative selection in plants. | 2004 Apr |
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| Intrahippocampal administration of the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats. | 2004 Jan |
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| Alpha-keto-beta-methylvaleric acid increases the in vitro phosphorylation of intermediate filaments in cerebral cortex of young rats through the gabaergic system. | 2004 Jan 15 |
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| Protective effect of alpha-keto-beta-methyl-n-valeric acid on BV-2 microglia under hypoxia or oxidative stress. | 2005 May |
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| Bioactive diterpenes from the fruits of Detarium microcarpum. | 2006 May |
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| Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy. | 2008 Aug 1 |
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| Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation. | 2009 Oct |
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| Metabolic changes reveal the development of schistosomiasis in mice. | 2010 Aug 31 |
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| The chemistry, pharmacologic, and therapeutic applications of Polyalthia longifolia. | 2010 Jan |
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| Pentanol isomer synthesis in engineered microorganisms. | 2010 Jan |
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| Compartmentalization of the Edinburgh Human Metabolic Network. | 2010 Jul 22 |
|
| Prediction of novel synthetic pathways for the production of desired chemicals. | 2010 Mar 28 |
|
| Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010 May |
Patents
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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JECFA EVALUATION |
3-METHYL-2-OXOPENTANOIC ACID
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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| Code System | Code | Type | Description | ||
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47
Created by
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453
Created by
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DTXSID50862670
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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787T50HCIV
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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3-ETHYL-3-METHYLPYRUVIC ACID
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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35932
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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1460-34-0
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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215-955-0
Created by
admin on Sat Dec 16 01:02:51 GMT 2023 , Edited by admin on Sat Dec 16 01:02:51 GMT 2023
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SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SUBSTANCE RECORD
