Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C6H9O3.Na |
| Molecular Weight | 152.1236 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CCC(C)C(=O)C([O-])=O
InChI
InChIKey=SMDJDLCNOXJGKC-UHFFFAOYSA-M
InChI=1S/C6H10O3.Na/c1-3-4(2)5(7)6(8)9;/h4H,3H2,1-2H3,(H,8,9);/q;+1/p-1
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H9O3 |
| Molecular Weight | 129.1339 |
| Charge | -1 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Metabolic changes reveal the development of schistosomiasis in mice. | 2010-08-31 |
|
| Compartmentalization of the Edinburgh Human Metabolic Network. | 2010-07-22 |
|
| Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato. | 2010-07 |
|
| Engineering Corynebacterium glutamicum for isobutanol production. | 2010-07 |
|
| Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010-05 |
|
| The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs. | 2010-04 |
|
| Prediction of novel synthetic pathways for the production of desired chemicals. | 2010-03-28 |
|
| Genome sequence of the pea aphid Acyrthosiphon pisum. | 2010-02-23 |
|
| The chemistry, pharmacologic, and therapeutic applications of Polyalthia longifolia. | 2010-01 |
|
| Pentanol isomer synthesis in engineered microorganisms. | 2010-01 |
|
| Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation. | 2009-10 |
|
| The role of free amino acids in semen of rainbow trout Oncorhynchus mykiss and carp Cyprinus carpio. | 2009-09 |
|
| Streptococcus pneumoniae and Staphylococcus aureus pneumonia induce distinct metabolic responses. | 2009-06 |
|
| Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy. | 2008-08-01 |
|
| NMR-spectroscopy-based metabonomic approach to the analysis of Bay41-4109, a novel anti-HBV compound, induced hepatotoxicity in rats. | 2007-09-28 |
|
| Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells. | 2007-09-15 |
|
| Synaptic plasma membrane Na(+), K (+)-ATPase activity is significantly reduced by the alpha-keto acids accumulating in maple syrup urine disease in rat cerebral cortex. | 2007-03 |
|
| Branched chain keto-acids exert biphasic effects on alpha-ketoglutarate-stimulated respiration in intact rat liver mitochondria. | 2007-01-10 |
|
| Bioactive diterpenes from the fruits of Detarium microcarpum. | 2006-05 |
|
| Hypobaric hypoxia affects endogenous levels of alpha-keto acids in murine heart ventricles. | 2006-04-14 |
|
| Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. | 2006-02 |
|
| Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in C6-glioma cells. | 2005-09 |
|
| Modeling Lactococcus lactis using a genome-scale flux model. | 2005-06-27 |
|
| alpha-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences in cerebral cortex from young rats. | 2005-06 |
|
| Protective effect of alpha-keto-beta-methyl-n-valeric acid on BV-2 microglia under hypoxia or oxidative stress. | 2005-05 |
|
| Branched-chain fatty acid biosynthesis in a branched-chain amino acid aminotransferase mutant of Staphylococcus carnosus. | 2005-02-01 |
|
| alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores. | 2004-12-01 |
|
| Evidence that the branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex. | 2004-11-15 |
|
| Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases. | 2004-08 |
|
| alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. | 2004-07 |
|
| A conditional marker gene allowing both positive and negative selection in plants. | 2004-04 |
|
| Alpha-keto-beta-methylvaleric acid increases the in vitro phosphorylation of intermediate filaments in cerebral cortex of young rats through the gabaergic system. | 2004-01-15 |
|
| Intrahippocampal administration of the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats. | 2004-01 |
|
| Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. | 2004 |
|
| Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease. | 2003-11-20 |
|
| Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. | 2003-10-15 |
|
| Biosynthesis of branched-chain fatty acid in bacilli: FabD (malonyl-CoA:ACP transacylase) is not essential for in vitro biosynthesis of branched-chain fatty acids. | 2003-10 |
|
| Substrate specificity and kinetic isotope effect analysis of the Eschericia coli ketopantoate reductase. | 2003-09-30 |
|
| Lacticin 3147 favours isoleucine transamination by Lactococcus lactis IFPL359 in a cheese-model system. | 2003-04 |
|
| Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. | 2003-01-20 |
|
| Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids. | 2003-01-14 |
|
| Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. | 2002-06 |
|
| Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. | 2001-03-09 |
|
| Determination of (S)- and (R)-2-oxo-3-methylvaleric acid in plasma of patients with maple syrup urine disease. | 1992-06-15 |
|
| Propionyl-CoA carboxylase deficiency with overflow of metabolites of isoleucine catabolism at all levels. | 1979-01-18 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:43:30 GMT 2025
by
admin
on
Mon Mar 31 20:43:30 GMT 2025
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| Record UNII |
2S329HH8M0
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| Record Status |
Validated (UNII)
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| Record Version |
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1469
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2S329HH8M0
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2724058
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223-063-8
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DTXSID30958348
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3715-31-9
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
